• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一家机构如何克服重重挑战,启动基于磁共振成像(MRI)的宫颈癌近距离放射治疗项目。

How one institution overcame the challenges to start an MRI-based brachytherapy program for cervical cancer.

作者信息

Harkenrider Matthew M, Shea Steven M, Wood Abbie M, Chinsky Bonnie, Bajaj Amishi, Mysz Michael, Yacoub Joseph H, Goldberg Ari, Liotta Margaret, Potkul Ronald, Surucu Murat, Roeske John, Small William

机构信息

Department of Radiation Oncology.

Department of Radiology.

出版信息

J Contemp Brachytherapy. 2017 Apr;9(2):177-186. doi: 10.5114/jcb.2017.66892. Epub 2017 Mar 30.

DOI:10.5114/jcb.2017.66892
PMID:28533808
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5437078/
Abstract

PURPOSE

Adaptive magnetic resonance imaging (MRI)-based brachytherapy results in improved local control and decreased high-grade toxicities compared to historical controls. Incorporating MRI into the workflow of a department can be a major challenge when initiating an MRI-based brachytherapy program. This project aims to describe the goals, challenges, and solutions when initiating an MRI-based cervical cancer brachytherapy program at our institution.

MATERIAL AND METHODS

We describe the 6-month multi-disciplinary planning phase to initiate an MRI-based brachytherapy program. We describe the specific challenges that were encountered prior to treating our first patient.

RESULTS

We describe the solutions that were realized and executed to solve the challenges that we faced to establish our MRI-based brachytherapy program. We emphasize detailed coordination of care, planning, and communication to make the workflow feasible. We detail the imaging and radiation physics solutions to safely deliver MRI-based brachytherapy. The focus of these efforts is always on the delivery of optimal, state of the art patient care and treatment delivery within the context of our available institutional resources.

CONCLUSIONS

Previous publications have supported a transition to MRI-based brachytherapy, and this can be safely and efficiently accomplished as described in this manuscript.

摘要

目的

与历史对照相比,基于自适应磁共振成像(MRI)的近距离放射治疗可改善局部控制并降低高级别毒性。在启动基于MRI的近距离放射治疗计划时,将MRI纳入科室工作流程可能是一项重大挑战。本项目旨在描述在我们机构启动基于MRI的宫颈癌近距离放射治疗计划时的目标、挑战和解决方案。

材料与方法

我们描述了启动基于MRI的近距离放射治疗计划的为期6个月的多学科规划阶段。我们描述了在治疗首例患者之前遇到的具体挑战。

结果

我们描述了为解决在建立基于MRI的近距离放射治疗计划过程中所面临的挑战而实现和执行的解决方案。我们强调精心协调护理、规划和沟通以使工作流程可行。我们详细介绍了安全实施基于MRI的近距离放射治疗的成像和放射物理学解决方案。这些努力始终聚焦于在我们现有的机构资源范围内提供最佳的、先进的患者护理和治疗。

结论

先前的出版物支持向基于MRI的近距离放射治疗过渡,并且如本手稿所述,这可以安全、高效地完成。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d14/5437078/762ee4f887eb/JCB-9-29708-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d14/5437078/4ae0820f024d/JCB-9-29708-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d14/5437078/3e27d1b41410/JCB-9-29708-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d14/5437078/8e9c72e6319d/JCB-9-29708-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d14/5437078/762ee4f887eb/JCB-9-29708-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d14/5437078/4ae0820f024d/JCB-9-29708-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d14/5437078/3e27d1b41410/JCB-9-29708-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d14/5437078/8e9c72e6319d/JCB-9-29708-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d14/5437078/762ee4f887eb/JCB-9-29708-g004.jpg

相似文献

1
How one institution overcame the challenges to start an MRI-based brachytherapy program for cervical cancer.一家机构如何克服重重挑战,启动基于磁共振成像(MRI)的宫颈癌近距离放射治疗项目。
J Contemp Brachytherapy. 2017 Apr;9(2):177-186. doi: 10.5114/jcb.2017.66892. Epub 2017 Mar 30.
2
Clinical implementation, logistics and workflow guide for MRI image based interstitial HDR brachytherapy for gynecological cancers.基于MRI图像的妇科癌症间质高剂量率近距离放射治疗的临床实施、后勤保障及工作流程指南
J Appl Clin Med Phys. 2019 Nov;20(11):37-49. doi: 10.1002/acm2.12736. Epub 2019 Oct 10.
3
Implementation and validation of a combined MRI-CT-based cervical cancer brachytherapy program using existing infrastructure.利用现有基础设施实施并验证基于MRI-CT联合的宫颈癌近距离治疗方案。
Brachytherapy. 2016 May-Jun;15(3):319-326. doi: 10.1016/j.brachy.2016.01.005.
4
TU-E-213CD-01: Image Guided Adaptive Brachytherapy for Cervical Cancer.TU-E-213CD-01:宫颈癌的图像引导自适应近距离放射治疗
Med Phys. 2012 Jun;39(6Part24):3913. doi: 10.1118/1.4735972.
5
Combining transrectal ultrasound and CT for image-guided adaptive brachytherapy of cervical cancer: Proof of concept.经直肠超声与CT联合用于宫颈癌图像引导下的适形近距离放疗:概念验证
Brachytherapy. 2016 Nov-Dec;15(6):839-844. doi: 10.1016/j.brachy.2016.08.009. Epub 2016 Sep 29.
6
Implementing MRI-based target delineation for cervical cancer treatment within a rapid workflow environment for image-guided brachytherapy: A practical approach for centers without in-room MRI.在用于图像引导近距离放疗的快速工作流程环境中实施基于MRI的宫颈癌治疗靶区勾画:针对没有室内MRI设备的中心的实用方法。
Brachytherapy. 2015 Nov-Dec;14(6):905-9. doi: 10.1016/j.brachy.2015.07.005. Epub 2015 Aug 29.
7
Workflow efficiency for the treatment planning process in CT-guided high-dose-rate brachytherapy for cervical cancer.宫颈癌CT引导下高剂量率近距离放射治疗中治疗计划流程的工作效率
Brachytherapy. 2016 Sep-Oct;15(5):578-83. doi: 10.1016/j.brachy.2016.06.001. Epub 2016 Jul 28.
8
Image-based brachytherapy for cervical cancer.基于图像的宫颈癌近距离放射治疗。
World J Clin Oncol. 2014 Dec 10;5(5):921-30. doi: 10.5306/wjco.v5.i5.921.
9
Impact on treatment time of MRI-based brachytherapy in two implants (4 doses) compared with CT-based brachytherapy in five implants for cervical cancer.与基于CT的近距离放射治疗(五个植入物)相比,基于MRI的近距离放射治疗(两个植入物,4次剂量)对宫颈癌治疗时间的影响。
Brachytherapy. 2019 Mar-Apr;18(2):141-145. doi: 10.1016/j.brachy.2018.10.005. Epub 2018 Nov 26.
10
Magnetic resonance imaging-guided brachytherapy for cervical cancer: initiating a program.磁共振成像引导下的宫颈癌近距离治疗:启动一个项目。
J Contemp Brachytherapy. 2015 Oct;7(5):417-22. doi: 10.5114/jcb.2015.55541. Epub 2015 Oct 30.

引用本文的文献

1
Analysis of operative duration of image-guided brachytherapy for cervical cancer.宫颈癌图像引导近距离放射治疗的手术时长分析。
Strahlenther Onkol. 2025 May;201(5):520-527. doi: 10.1007/s00066-024-02297-5. Epub 2024 Sep 16.
2
High-Dose-Rate Three-Dimensional Image-Guided Adaptive Brachytherapy (3D IGABT) for Locally Advanced Cervical Cancer (LACC): A Narrative Review on Imaging Modality and Clinical Evidence.高剂量率三维影像引导自适应近距离放射治疗用于局部晚期宫颈癌:关于成像方式和临床证据的叙述性综述
Curr Oncol. 2023 Dec 21;31(1):50-65. doi: 10.3390/curroncol31010004.
3
Dosimetric impact of applicator displacement on three-dimensional image-guided high-dose-rate brachytherapy treatments for cervical cancer.

本文引用的文献

1
Metal artefacts in MRI-guided brachytherapy of cervical cancer.宫颈癌磁共振成像引导近距离放射治疗中的金属伪影
J Contemp Brachytherapy. 2016 Aug;8(4):363-9. doi: 10.5114/jcb.2016.61817. Epub 2016 Aug 16.
2
Implementation and validation of a combined MRI-CT-based cervical cancer brachytherapy program using existing infrastructure.利用现有基础设施实施并验证基于MRI-CT联合的宫颈癌近距离治疗方案。
Brachytherapy. 2016 May-Jun;15(3):319-326. doi: 10.1016/j.brachy.2016.01.005.
3
The use of MRI deformable image registration for CT-based brachytherapy in locally advanced cervical cancer.
施源器位移对宫颈癌三维图像引导高剂量率近距离放射治疗剂量学的影响
J Contemp Brachytherapy. 2023 Oct;15(5):334-343. doi: 10.5114/jcb.2023.132697. Epub 2023 Oct 31.
4
Transitioning India to advanced image based adaptive brachytherapy: a national impact analysis of upgrading National Cancer Grid cervix cancer guidelines.将印度过渡到基于先进影像的自适应近距离放射治疗:对升级国家癌症网格宫颈癌指南的全国影响分析。
Lancet Reg Health Southeast Asia. 2023 Jun 6;16:100218. doi: 10.1016/j.lansea.2023.100218. eCollection 2023 Sep.
5
Development of a multi-purpose quality control phantom for MRI-based treatment planning in high-dose-rate brachytherapy of cervical cancer.用于宫颈癌高剂量率近距离放射治疗中基于MRI的治疗计划的多功能质量控制体模的研制。
J Contemp Brachytherapy. 2023 Feb;15(1):57-68. doi: 10.5114/jcb.2023.125014. Epub 2023 Feb 10.
6
Analysis of Applicator Insertion Related Acute Side Effects for Cervical Cancer Treated With Brachytherapy.近距离放射治疗宫颈癌时施源器插入相关急性副作用的分析
Front Oncol. 2021 Jun 7;11:677052. doi: 10.3389/fonc.2021.677052. eCollection 2021.
7
Radical radiotherapy in patients with cervix uteri carcinoma: experience of Ondokuz Mayis University.子宫颈癌患者的根治性放疗:安卡拉大学的经验。
BMC Cancer. 2019 Dec 12;19(1):1208. doi: 10.1186/s12885-019-6402-x.
8
Comparison of impact of target delineation of computed tomography- and magnetic resonance imaging-guided brachytherapy on dose distribution in cervical cancer.计算机断层扫描和磁共振成像引导下近距离放射治疗的靶区勾画对宫颈癌剂量分布影响的比较
J Contemp Brachytherapy. 2018 Oct;10(5):418-424. doi: 10.5114/jcb.2018.78993. Epub 2018 Oct 15.
9
Off-line magnetic resonance imaging navigation of cervix cancer brachytherapy in patients with risk factors for uterine perforation.子宫穿孔风险因素患者宫颈癌近距离治疗的离线磁共振成像导航
J Contemp Brachytherapy. 2017 Dec;9(6):519-526. doi: 10.5114/jcb.2017.71912. Epub 2017 Dec 30.
10
Throwing the dart blind-folded: comparison of computed tomography versus magnetic resonance imaging-guided brachytherapy for cervical cancer with regard to dose received by the 'actual' targets and organs at risk.蒙眼掷镖:计算机断层扫描与磁共振成像引导下宫颈癌近距离放疗在“实际”靶区和危及器官所接受剂量方面的比较
J Contemp Brachytherapy. 2017 Oct;9(5):446-452. doi: 10.5114/jcb.2017.71050. Epub 2017 Oct 30.
磁共振成像(MRI)可变形图像配准在局部晚期宫颈癌基于CT的近距离放射治疗中的应用。
Brachytherapy. 2016 May-Jun;15(3):333-340. doi: 10.1016/j.brachy.2016.01.002. Epub 2016 Feb 13.
4
Value of Magnetic Resonance Imaging Without or With Applicator in Place for Target Definition in Cervix Cancer Brachytherapy.磁共振成像(MRI)在宫颈癌近距离放疗中置管前后靶区勾画的价值
Int J Radiat Oncol Biol Phys. 2016 Mar 1;94(3):588-97. doi: 10.1016/j.ijrobp.2015.09.023.
5
Magnetic resonance imaging-guided brachytherapy for cervical cancer: initiating a program.磁共振成像引导下的宫颈癌近距离治疗:启动一个项目。
J Contemp Brachytherapy. 2015 Oct;7(5):417-22. doi: 10.5114/jcb.2015.55541. Epub 2015 Oct 30.
6
Implementing MRI-based target delineation for cervical cancer treatment within a rapid workflow environment for image-guided brachytherapy: A practical approach for centers without in-room MRI.在用于图像引导近距离放疗的快速工作流程环境中实施基于MRI的宫颈癌治疗靶区勾画:针对没有室内MRI设备的中心的实用方法。
Brachytherapy. 2015 Nov-Dec;14(6):905-9. doi: 10.1016/j.brachy.2015.07.005. Epub 2015 Aug 29.
7
Image-Based Brachytherapy for the Treatment of Cervical Cancer.基于图像的宫颈癌近距离治疗。
Int J Radiat Oncol Biol Phys. 2015 Jul 15;92(4):921-34. doi: 10.1016/j.ijrobp.2015.03.010.
8
Caudal epidural anesthesia during intracavitary brachytherapy for cervical cancer.宫颈癌腔内近距离放疗期间的骶管硬膜外麻醉
J Radiat Res. 2015 May;56(3):583-7. doi: 10.1093/jrr/rrv011. Epub 2015 Apr 6.
9
MRI-guided high-dose-rate intracavitary brachytherapy for treatment of cervical cancer: the University of Pittsburgh experience.MRI引导下高剂量率腔内近距离放射治疗宫颈癌:匹兹堡大学的经验
Int J Radiat Oncol Biol Phys. 2015 Mar 1;91(3):540-7. doi: 10.1016/j.ijrobp.2014.10.053. Epub 2015 Jan 30.
10
Optimizing packing contrast for MRI-based intracavitary brachytherapy planning for cervical cancer.优化基于MRI的宫颈癌腔内近距离放射治疗计划的填充对比度。
Brachytherapy. 2015 May-Jun;14(3):385-9. doi: 10.1016/j.brachy.2014.12.005. Epub 2015 Jan 22.