Fukino Nobutada, Oida Takatsugu, Mimatsu Kenji, Kuboi Youichi, Kida Kazutoshi
Nobutada Fukino, Takatsugu Oida, Kenji Mimatsu, Youichi Kuboi, Kazutoshi Kida, Department of Surgery, Japan Community Healthcare Organization Yokohama Central Hospital, Kanagawa 231-8553, Japan.
World J Gastroenterol. 2015 Apr 7;21(13):4082-8. doi: 10.3748/wjg.v21.i13.4082.
A 62-year-old Japanese man presented to our hospital with a history of weight loss of 6 kg in 4 mo. Imaging examinations revealed a tumor located on the third portion of the duodenum with stenosis. We suspected duodenal carcinoma and performed pancreas-preserving segmental duodenectomy. Adenocarcinoma arising from a heterotopic pancreas at the third portion of the duodenum was finally diagnosed by immunohistochemical staining. Malignant transformation in the duodenum arising from a heterotopic pancreas is extremely rare; to our knowledge, only 13 cases have been reported worldwide, including the present case. The most common location of malignancy is the proximal duodenum at the first and descending portion. Herein, we describe the first case of adenocarcinoma arising from a heterotopic pancreas, which was located in the third portion of the duodenum, with a review of the literature.
一名62岁的日本男性因在4个月内体重减轻6公斤的病史前来我院就诊。影像学检查发现十二指肠第三段有一个伴有狭窄的肿瘤。我们怀疑是十二指肠癌,并进行了保留胰腺的节段性十二指肠切除术。最终通过免疫组织化学染色诊断为十二指肠第三段异位胰腺发生的腺癌。异位胰腺在十二指肠发生恶性转化极为罕见;据我们所知,包括本病例在内,全世界仅报道了13例。恶性肿瘤最常见的部位是十二指肠第一段和降部的近端。在此,我们描述了首例发生于十二指肠第三段的异位胰腺腺癌病例,并对文献进行了回顾。