欧洲的肾脏替代治疗：2011年欧洲肾脏协会-欧洲透析与移植协会登记处年度报告摘要
Renal replacement therapy in Europe: a summary of the 2011 ERA-EDTA Registry Annual Report.
作者信息
Noordzij Marlies, Kramer Anneke, Abad Diez José M, Alonso de la Torre Ramón, Arcos Fuster Emma, Bikbov Boris T, Bonthuis Marjolein, Bouzas Caamaño Encarnación, Čala Svetlana, Caskey Fergus J, Castro de la Nuez Pablo, Cernevskis Harijs, Collart Frederic, Díaz Tejeiro Rafael, Djukanovic Ljubica, Ferrer-Alamar Manuel, Finne Patrik, García Bazaga María de Los Angelos, Garneata Liliana, Golan Eliezer, Gonzalez Fernández Raquel, Heaf James G, Hoitsma Andries, Ioannidis George A, Kolesnyk Mykola, Kramar Reinhard, Lasalle Mathilde, Leivestad Torbjørn, Lopot Frantisek, van de Luijtgaarden Moniek W M, Macário Fernando, Magaz Ángela, Martín Escobar Eduardo, de Meester Johan, Metcalfe Wendy, Ots-Rosenberg Mai, Palsson Runolfur, Piñera Celestino, Pippias Maria, Prütz Karl G, Ratkovic Marina, Resić Halima, Rodríguez Hernández Aurelio, Rutkowski Boleslaw, Spustová Viera, Stel Vianda S, Stojceva-Taneva Olivera, Süleymanlar Gültekin, Wanner Christoph, Jager Kitty J
机构信息
ERA-EDTA Registry, Department of Medical Informatics , Academic Medical Center, University of Amsterdam , Amsterdam , the Netherlands.
Planificación y Aseguramiento , Gobierno de Aragón , Aragon , Spain.
出版信息
Clin Kidney J. 2014 Apr;7(2):227-38. doi: 10.1093/ckj/sfu007. Epub 2014 Mar 2.
BACKGROUND
This article provides a summary of the 2011 ERA-EDTA Registry Annual Report (available at www.era-edta-reg.org).
METHODS
Data on renal replacement therapy (RRT) for end-stage renal disease (ESRD) from national and regional renal registries in 30 countries in Europe and bordering the Mediterranean Sea were used. From 27 registries, individual patient data were received, whereas 17 registries contributed data in aggregated form. We present the incidence and prevalence of RRT, and renal transplant rates in 2011. In addition, survival probabilities and expected remaining lifetimes were calculated for those registries providing individual patient data.
RESULTS
The overall unadjusted incidence rate of RRT in 2011 among all registries reporting to the ERA-EDTA Registry was 117 per million population (pmp) (n = 71.631). Incidence rates varied from 24 pmp in Ukraine to 238 pmp in Turkey. The overall unadjusted prevalence of RRT for ESRD on 31 December 2011 was 692 pmp (n = 425 824). The highest prevalence was reported by Portugal (1662 pmp) and the lowest by Ukraine (131 pmp). Among all registries, a total of 22 814 renal transplantations were performed (37 pmp). The highest overall transplant rate was reported from Spain, Cantabria (81 pmp), whereas the highest rate of living donor transplants was reported from Turkey (39 pmp). For patients who started RRT between 2002 and 2006, the unadjusted 5-year patient survival on RRT was 46.8% [95% confidence interval (CI) 46.6-47.0], and on dialysis 39.3% (95% CI 39.2-39.4). The unadjusted 5-year patient survival after the first renal transplantation performed between 2002 and 2006 was 86.7% (95% CI 86.2-87.2) for kidneys from deceased donors and 94.3% (95% CI 93.6-95.0) for kidneys from living donors.
背景
本文总结了2011年欧洲肾脏协会-欧洲透析移植协会（ERA-EDTA）注册中心年度报告（可在www.era-edta-reg.org获取）。
方法
使用了来自欧洲30个国家及地中海周边国家的国家和地区肾脏注册中心的终末期肾病（ESRD）肾脏替代治疗（RRT）数据。从27个注册中心接收了个体患者数据，而17个注册中心以汇总形式提供数据。我们展示了2011年RRT的发病率和患病率以及肾移植率。此外，还为那些提供个体患者数据的注册中心计算了生存概率和预期剩余寿命。
结果
向ERA-EDTA注册中心报告的所有注册中心中，2011年RRT的总体未调整发病率为每百万人口117例（pmp）（n = 71,631）。发病率从乌克兰的每百万人口24例到土耳其的每百万人口238例不等。2011年12月31日ESRD的RRT总体未调整患病率为每百万人口692例（n = 425,824）。葡萄牙报告的患病率最高（每百万人口1662例），乌克兰最低（每百万人口131例）。在所有注册中心中，共进行了22,814例肾移植（每百万人口37例）。西班牙坎塔布里亚报告的总体移植率最高（每百万人口81例），而土耳其报告的活体供肾移植率最高（每百万人口39例）。对于2002年至2006年间开始接受RRT的患者，RRT的未调整5年患者生存率为46.8% [95%置信区间（CI）46.6 - 47.0]，透析患者为39.3%（95% CI 39.2 - 39.4）。2002年至2006年间首次进行肾移植后，来自 deceased donors的肾脏的未调整5年患者生存率为86.7%（95% CI 86.2 - 87.2）；来自活体供肾的肾脏为94.3%（95% CI 93.6 - 95.0）。
Zotero 插件