Department of Medical Gastroenterology and Hepatology 3163, Rigshospitalet, Inge Lehmanns Vej 7, 2100, Copenhagen, Denmark.
Dig Dis Sci. 2019 Oct;64(10):2717-2735. doi: 10.1007/s10620-019-05779-0.
The ability to provide parenteral support represents a revolutionary change in medical therapy for patients with temporary and inadequate intestinal absorptive capacity or for patients with chronic intestinal failure due to digestive diseases. Nevertheless, due to the rarity of intestinal failure, a de facto policy of "discrimination by organ failure treatment" exists in many countries whereby this problem is under-recognized and under-treated. With the increasing recognition of the pathophysiological consequences of intestinal resection and the occurrence of new pro-adaptive treatments for patients suffering from short bowel syndrome, this review reflects on the history of developments in this area and discusses current practice and future directions of the field.
提供肠外支持的能力代表了对暂时和吸收能力不足的肠道患者或因消化疾病导致慢性肠道衰竭的患者进行医学治疗的革命性变化。然而，由于肠道衰竭的罕见性，许多国家实际上存在“按器官衰竭治疗进行歧视”的政策，从而导致对这个问题的认识不足和治疗不足。随着对肠道切除的病理生理后果的认识不断提高，以及对患有短肠综合征的患者的新适应性治疗方法的出现，本综述反思了这一领域的发展历史，并讨论了该领域的当前实践和未来方向。
