Raissy Hengameh, Blake Kathryn
Department of Pediatrics, School of Medicine, University of New Mexico , Albuquerque, New Mexico.
Biomedical Research Department, Nemours Children's Clinic , Jacksonville, Florida.
Pediatr Allergy Immunol Pulmonol. 2015 Mar 1;28(1):60-62. doi: 10.1089/ped.2014.0444.
Many observational studies have investigated the potential association between vitamin D and asthma. However, it is difficult to find a temporal causal relationship in cross-sectional or observational studies. This review presents recent clinical trials and the evidence of association between vitamin D and asthma in different patient populations and asthma status. Well-designed clinical trials are warranted in order to define the optimal level of vitamin D, as well as dosing and duration of vitamin D supplementation, in pediatric patients.
许多观察性研究已调查了维生素D与哮喘之间的潜在关联。然而，在横断面研究或观察性研究中很难找到时间上的因果关系。本综述介绍了近期的临床试验以及不同患者群体和哮喘状态下维生素D与哮喘之间关联的证据。为了确定儿科患者维生素D的最佳水平以及维生素D补充的剂量和持续时间，有必要开展设计良好的临床试验。
