烟雾病一例中的功能性皮质和小脑重组
Functional cortical and cerebellar reorganization in a case of moyamoya disease.
作者信息
Calabrò Rocco S, Bramanti Placido, Baglieri Annalisa, Corallo Francesco, De Luca Rosaria, De Salvo Simona, Marino Silvia
机构信息
All from IRCCS Centro Neurolesi Bonino-Pulejo, Messina, Italy.
出版信息
Innov Clin Neurosci. 2015 Jan-Feb;12(1-2):24-8.
BACKGROUND
Functional studies have been previous reported in stroke patients, but no studies of functional magnetic resonance imaging have been performed in Moyamoya disease.
OBJECTIVE
To assess the cortical and cerebellar reorganization in a moyamoya patient.
METHODS
We reported a case of a patient suffering from moyamoya disease, undergoing a neuropsychological assessment, a neurocognitive rehabilitative treatment, an electroencephalogram evaluation, and a functional magnetic resonance imaging examination.
RESULTS
The subject showed a cognitive impairment, a slow electroencephalogram activity, and the ipsi- and controlateral motor cortex and cerebellar functional magnetic resonance imaging activation.
CONCLUSIONS
This is the first functional magnetic resonance imaging case study reported in moyamoya disease. We showed a cortical reorganization, which could play an important role in clinical evaluation and motor recovery. The cerebellar activation, showed after cognitive and motor rehabilitation, could support the idea that the cerebellum contains several cognitive-related subregions involved in different functional networks in moyamoya disease.
背景
此前已有针对中风患者的功能研究报告，但尚未对烟雾病患者进行功能磁共振成像研究。
目的
评估一名烟雾病患者的皮质和小脑重组情况。
方法
我们报告了一例烟雾病患者，该患者接受了神经心理学评估、神经认知康复治疗、脑电图评估以及功能磁共振成像检查。
结果
该受试者表现出认知障碍、脑电图活动缓慢，以及同侧和对侧运动皮质及小脑功能磁共振成像激活。
结论
这是首次报道的烟雾病功能磁共振成像病例研究。我们展示了皮质重组，其可能在临床评估和运动恢复中发挥重要作用。认知和运动康复后出现的小脑激活，可能支持小脑包含参与烟雾病不同功能网络的多个认知相关亚区域这一观点。
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