Sun Lihong, Liang Yulei, Li Xinhua, Liu Li, Xu Xiaokang, Ma Hongli, Li Wenli, Gao Fei
Zhongguo Zhen Jiu. 2015 Feb;35(2):137-40.
To observe the clinical efficacy of acupuncture combined with auricular point sticking for menstrual headache and to discuss its mechanism.
Eighty-five patients with menstrual headache were randomly divided into an observation group (43 cases) and a control group (42 cases). The observation group was treated with body acupuncture combined with auricular point sticking and the control group was treated with flunarizine hydrochloride capsules orally. The treatments of 3 menstrual cycles were required. The clinical efficacy was observed in the two groups. The content of serum prostaglandin F2α, (PGF2α) and plasma arginine vasopressin (AVP) in the menstrual periods of some patients randomly selected in the two groups was tested before and after treatment and was compared with that of 20 cases in a normal group. Results The total effective rate was 95.4% (41/43) in the observation group which was obviously superior to 81.0% (34/42) in the control group (P<0.01). Before treatment, the content of serum PGF2α and plasma AVP of patients in the two groups was higher than that in the normal group (all P<0.01). After treatment,the content of serum PGF2α and plasma AVP was lower than that before treatment in the two groups (P<0.01, P<0.05). The content of serum PGF2α in the observation group was decreased significantly compared with that in the control group (P<0.05) and returned to the level of the normal group.
Body acupuncture combined with auricular point sticking achieves positive efficacy for menstrual headache and its mechanism could be related to regulating the abnormal levels of serum PGF2α and plasma AVP.
观察针刺联合耳穴贴压治疗经期头痛的临床疗效并探讨其作用机制。
将85例经期头痛患者随机分为观察组（43例）和对照组（42例）。观察组采用体针联合耳穴贴压治疗，对照组口服盐酸氟桂利嗪胶囊治疗。两组均需治疗3个月经周期。观察两组临床疗效。随机选取两组部分患者，检测其治疗前后经期血清前列腺素F2α（PGF2α）含量及血浆精氨酸加压素（AVP）水平，并与正常组20例进行比较。结果观察组总有效率为95.4%（41/43），明显优于对照组的81.0%（34/42）（P<0.01）。治疗前，两组患者血清PGF2α含量及血浆AVP水平均高于正常组（均P<0.01）。治疗后，两组血清PGF2α含量及血浆AVP水平均低于治疗前（P<0.01，P<0.05）。观察组血清PGF2α含量较对照组明显降低（P<0.05），并恢复至正常组水平。
体针联合耳穴贴压治疗经期头痛疗效确切，其机制可能与调节血清PGF2α及血浆AVP异常水平有关。
