pH 敏感型金纳米簇：用于尿素、脲酶及脲酶抑制剂检测的制备方法与分析应用
pH-Sensitive gold nanoclusters: preparation and analytical applications for urea, urease, and urease inhibitor detection.
作者信息
Deng Hao-Hua, Wu Gang-Wei, Zou Zhi-Qiang, Peng Hua-Ping, Liu Ai-Lin, Lin Xin-Hua, Xia Xing-Hua, Chen Wei
机构信息
Department of Pharmaceutical Analysis, Fujian Medical University, Fuzhou 350004, China.
出版信息
Chem Commun (Camb). 2015 May 7;51(37):7847-50. doi: 10.1039/c5cc00702j.
PMID:25854314
Abstract
Herein, we reported for the first time a facile synthetic process of gold nanoclusters (AuNCs) by using N-acetyl-L-cysteine both as a reducing agent and as a protection ligand. Based on the pH stimuli-responsive properties of the as-prepared AuNCs, we constructed a pH-sensing platform for the detection of urea, urease, and urease inhibitors.
摘要
在此，我们首次报道了一种简便的金纳米簇（AuNCs）合成方法，该方法使用N-乙酰-L-半胱氨酸作为还原剂和保护配体。基于所制备的AuNCs的pH刺激响应特性，我们构建了一个用于检测尿素、脲酶和脲酶抑制剂的pH传感平台。
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