Lynch Jeremy A
Department of Biological Sciences, University of Illinois at Chicago, Chicago, Illinois 60607
Genetics. 2015 Apr;199(4):897-904. doi: 10.1534/genetics.112.147512.
The parasitoid wasp Nasonia represents a genus of four species that is emerging as a powerful genetic model system that has made and will continue to make important contributions to our understanding of evolutionary biology, development, ecology, and behavior. Particularly powerful are the haplodiploid genetics of the system, which allow some of the advantages of microbial genetics to be applied to a complex multicellular eukaryote. In addition, fertile, viable hybrids can be made among the four species in the genus. This makes Nasonia exceptionally well suited for evolutionary genetics approaches, especially when combined with its haploid genetics and tractability in the laboratory. These features are complemented by an expanding array of genomic, transcriptomic, and functional resources, the application of which has already made Nasonia an important model system in such emerging fields as evolutionary developmental biology and microbiomics. This article describes the genetic and genomic advantages of Nasonia wasps and the resources available for their genetic analysis.
丽蝇蛹集金小蜂是一个包含四个物种的属，正逐渐成为一个强大的遗传模型系统，已经并将继续为我们理解进化生物学、发育、生态学和行为学做出重要贡献。该系统的单倍二倍体遗传学尤其强大，它使微生物遗传学的一些优势能够应用于复杂的多细胞真核生物。此外，该属的四个物种之间可以产生可育、有活力的杂种。这使得丽蝇蛹集金小蜂特别适合采用进化遗传学方法，尤其是结合其单倍体遗传学和在实验室中的易处理性时。这些特性得到了越来越多的基因组、转录组和功能资源的补充，这些资源的应用已经使丽蝇蛹集金小蜂成为进化发育生物学和微生物组学等新兴领域中的重要模型系统。本文描述了丽蝇蛹集金小蜂的遗传和基因组优势以及可用于其遗传分析的资源。
