Djelantik M, Bloemkolk D, Tijdink J
Tijdschr Psychiatr. 2015;57(3):210-4.
Wernicke encephalopathy is an acute neuropsychiatric disease with heterogeneous symptoms, including changes in mental status, ataxia and ocular abnormalities; if left untreated, these symptoms can lead to morbidity and even to mortality. The treatment is thiamine suppletion. Because of the heterogeneity of the symptoms and the high risk of morbidity and mortality if the symptoms are not treated, it is vitally important that on observing a patient's early symptoms the clinician immediately suspects that the symptoms could point to Wernicke encephalopathy.
韦尼克脑病是一种急性神经精神疾病,症状多样,包括精神状态改变、共济失调和眼部异常;若不治疗,这些症状可导致发病甚至死亡。治疗方法是补充硫胺素。由于症状的多样性以及不治疗时发病和死亡风险高,临床医生在观察到患者早期症状时立即怀疑这些症状可能指向韦尼克脑病至关重要。