Abdullah Mohamed Ruslan, Goharian Amirhossein, Abdul Kadir Mohammed Rafiq, Wahit Mat Uzir
Centre for Composites, Department of Applied Mechanics and Design, Universiti Teknologi Malaysia (UTM), 81310, Skudai, Johor, Malaysia.
Medical Devices & Technology Group, Faculty of Biosciences & Medical Engineering, Universiti Teknologi Malaysia (UTM), 81310, Skudai, Johor, Malaysia.
J Biomed Mater Res A. 2015 Nov;103(11):3689-702. doi: 10.1002/jbm.a.35480. Epub 2015 Apr 28.
The use of polyetheretherketone (PEEK) composites in the trauma plating system, total replacement implants, and tissue scaffolds has found great interest among researchers. In recent years (2008 afterward), this type of composites has been examined for suitability as substitute material over stainless steel, titanium alloys, ultra high molecular weight polyethylene, or even biodegradable materials in orthopedic implant applications. Biomechanical and bioactivity concepts were contemplated for the development of PEEK orthopedic implants and a few primary clinical studies reported the clinical outcomes of PEEK-based orthopedic implants. This study aims to review and discuss the recent concepts and contribute further concepts in terms of biomechanical and bioactivity challenges for the development of PEEK and PEEK composites in orthopedic implants.
聚醚醚酮（PEEK）复合材料在创伤接骨板系统、全置换植入物和组织支架中的应用引起了研究人员的极大兴趣。近年来（2008年之后），这种类型的复合材料已被研究作为不锈钢、钛合金、超高分子量聚乙烯甚至生物可降解材料在骨科植入应用中的替代材料的适用性。在聚醚醚酮骨科植入物的开发中考虑了生物力学和生物活性概念，一些初步临床研究报告了聚醚醚酮基骨科植入物的临床结果。本研究旨在回顾和讨论近期概念，并就在骨科植入物中开发聚醚醚酮和聚醚醚酮复合材料所面临的生物力学和生物活性挑战提出进一步的概念。
