Ueda W, Yokoyama M, Tsuchiya M, Tomoda M
Masui. 1989 Oct;38(10):1349-54.
The pharmacokinetics of intravenous drugs used during anesthesia provides us important information for patients' care. The pharmacokinetic data are usually shown in a graphic expression together with numerical values. The numerical values are only convenient for investigators in exchanging their knowledge and information. The graphic data contain, however, whole and real information obtained in a pharmacokinetic study. The authors demonstrated a way to derive information from graphic data, which is practically applicable for patients' care. We also showed a way to calculate numerical values from graphic data by using "graphnote" by Fukutake Pub. Co. We believe that our manual way to calculate numerical values from graphic data, with an aid of computer graphics combined with scientific calculator, helps us to understand the invisible processes performed inside "a black box" or a computer installed with a commercially available soft ware for the pharmacokinetics.
麻醉期间使用的静脉药物的药代动力学为患者护理提供了重要信息。药代动力学数据通常以图形表示并伴有数值。这些数值仅便于研究人员交流他们的知识和信息。然而，图形数据包含了药代动力学研究中获得的完整和真实信息。作者展示了一种从图形数据中获取信息的方法，该方法在实际中适用于患者护理。我们还展示了一种使用芙蓉出版社的“Graphnote”从图形数据中计算数值的方法。我们相信，借助计算机图形学和科学计算器，我们从图形数据中手动计算数值的方法有助于我们理解在“黑匣子”或安装有市售药代动力学软件的计算机内部进行的不可见过程。
