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2007 - 2012年韩国国家健康与营养检查调查:乙肝表面抗原阳性成年人中与乙肝表面抗原血清阳性未察觉相关的性别差异

Sex differences associated with hepatitis B virus surface antigen seropositivity unwareness in hepatitis B virus surface antigen-positive adults: 2007-2012 Korea National Health and Nutrition Examination Survey.

作者信息

Jang Suk-Yong, Jang Sung-In, Bae Hong-Chul, Shin Jaeyong, Park Eun-Cheol

机构信息

Department of Preventive Medicine, Yonsei University College of Medicine, Seoul, Korea ; Institute of Health Services Research, Yonsei University College of Medicine, Seoul, Korea.

出版信息

J Prev Med Public Health. 2015 Mar;48(2):74-83. doi: 10.3961/jpmph.14.034. Epub 2015 Mar 16.

DOI:10.3961/jpmph.14.034
PMID:25857645
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4398152/
Abstract

OBJECTIVES

To examine the sex-specific factors associated with being unaware of one's hepatitis B virus surface antigen (HBsAg) seropositivity status in a large, HBsAg-positive population of Koreans.

METHODS

In total, 1197 subjects aged 19 years or older who were HBsAg-positive according to data from the 2007-2012 Korea National Health and Nutrition Examination Survey were included. Subjects were considered unaware of their HBsAg seropositivity status if they answered that they had no knowledge of being previously infected by the hepatitis B virus (HBV) or diagnosed with HBV hepatitis. Multivariate Poisson regression models with robust variance estimate were used to assess the significance of the variables using weighted frequencies.

RESULTS

The majority (77.8%) of HbsAg-positive Korean adults (females, 81.9%; males, 74.6%) were unaware of their HBsAg seropositivity status. We found that sex (female: prevalence ratio [PR] 1.19), household income (low: PR, 1.15), marital status (never married: PR, 1.18), self-rated health (moderate: PR, 1.14; good: PR, 1.12), and alcohol use (at least 2-3 times/wk: PR, 1.21) were associated with being unaware. In females, age (50 to 59 years: PR, 1.29; ≥ 70 years: PR, 1.30), household income (low: PR, 1.37; middle-low: PR, 1.24), and marital status (never married: PR, 1.33) were associated with being unaware. In males, self-rated health (moderate: PR, 1.14; good: PR, 1.21) and alcohol use (at least 2-3 times/wk: PR, 1.21) were associated with being unaware.

CONCLUSIONS

Factors related to the socioeconomic status of females and the health-related behaviors of males were found to be associated with being unaware of one's HBsAg seropositivity status.

摘要

目的

在大量韩国乙肝表面抗原(HBsAg)阳性人群中,研究与未意识到自身HBsAg血清学阳性状态相关的性别特异性因素。

方法

根据2007 - 2012年韩国国家健康与营养检查调查数据,纳入了1197名19岁及以上的HBsAg阳性受试者。如果受试者回答他们不知道自己曾感染乙肝病毒(HBV)或被诊断为HBV肝炎,则被视为未意识到自身HBsAg血清学阳性状态。使用具有稳健方差估计的多变量泊松回归模型,通过加权频率评估变量的显著性。

结果

大多数(77.8%)HBsAg阳性的韩国成年人(女性为81.9%,男性为74.6%)未意识到自身HBsAg血清学阳性状态。我们发现,性别(女性:患病率比[PR]为1.19)、家庭收入(低:PR为1.15)、婚姻状况(未婚:PR为1.18)、自我评估健康状况(中等:PR为1.14;良好:PR为1.12)以及饮酒情况(每周至少2 - 3次:PR为1.21)与未意识到自身状态相关。在女性中,年龄(50至59岁:PR为1.29;≥70岁:PR为1.30)、家庭收入(低:PR为1.37;中低:PR为1.24)和婚姻状况(未婚:PR为1.33)与未意识到自身状态相关。在男性中,自我评估健康状况(中等:PR为1.14;良好:PR为1.21)和饮酒情况(每周至少2 - 3次:PR为1.21)与未意识到自身状态相关。

结论

发现与女性社会经济地位和男性健康相关行为有关的因素与未意识到自身HBsAg血清学阳性状态相关。

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