Tay Sammy C K, Badu Kingsley, Mensah Anthony A, Gbedema Stephen Y
Ann Clin Microbiol Antimicrob. 2015 Mar 7;14:10. doi: 10.1186/s12941-015-0064-6.
Malaria and HIV/AIDS are the two most common infections in sub-Sahara Africa. There are hypotheses and study reports on the possible association between these two infections, hence the prevalence and outcome of their co-infection in an endemic population will be important in defining healthcare strategies. A cross sectional study was carried out at the Holy Family Hospital in Techiman, Ghana, between November 2011 and January 2012, to determine the prevalence of malaria among HIV sero-positive patients and its impact on hemoglobin levels.
A total of 400 HIV sero-positive participants (292 females and 108 males) aged between 1 and 73 years were randomly sampled for the study. A questionnaire was administered and 2 ml of venous blood samples were drawn for malaria parasites detection, CD4 count and haemoglobin level estimations.
Malaria parasites were detected in 47 (11.75%) of the participants. There was no statistically significant difference between the malaria prevalence rate of females (12.1%) and males (10.2%) P = 0.6047. An overall anaemia prevalence of 67% was observed. Among participants with malaria the anaemia prevalence was 93.6%. The CD4 cell count of all the participants ranged between 3 and 1604 cells/μl with a mean of 386.2 (±274.3) cells/μl. Participants with malaria had CD4 cell count ranged 3 and 512 Cells/μl with the mean being 186.33 (±133.49) Cells/μl. Out of 377 participants (all above 15 years) interviewed on knowledge of malaria transmission and prevention, 87.0% had knowledge on transmission but only 8.5% use in bed nets.
It was revealed that almost all the patients with malaria infection were anemic.
疟疾和艾滋病毒/艾滋病是撒哈拉以南非洲最常见的两种感染。关于这两种感染之间可能存在的关联已有一些假设和研究报告，因此，在地方病流行人群中这两种感染的共感染率及后果对于确定医疗保健策略至关重要。2011年11月至2012年1月期间，在加纳特奇曼的圣家医院开展了一项横断面研究，以确定艾滋病毒血清阳性患者中的疟疾患病率及其对血红蛋白水平的影响。
本研究共随机抽取了400名年龄在1至73岁之间的艾滋病毒血清阳性参与者（292名女性和108名男性）。进行问卷调查，并采集2毫升静脉血样用于检测疟原虫、进行CD4细胞计数和血红蛋白水平评估。
47名（11.75%）参与者检测到疟原虫。女性（12.1%）和男性（10.2%）的疟疾患病率无统计学显著差异，P = 0.6047。观察到总体贫血患病率为67%。疟疾患者中的贫血患病率为93.6%。所有参与者的CD4细胞计数在3至1604个细胞/微升之间，平均为386.2（±274.3）个细胞/微升。患疟疾的参与者CD4细胞计数在3至512个细胞/微升之间，平均为186.33（±133.49）个细胞/微升。在接受疟疾传播和预防知识访谈的377名参与者（均为15岁以上）中，87.0%了解传播知识，但只有8.5%使用蚊帐。
结果显示，几乎所有疟疾感染患者都患有贫血。
