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埃及青少年曲马多的使用与滥用情况。

Adolescent tramadol use and abuse in Egypt.

作者信息

Bassiony Medhat M, Salah El-Deen Ghada M, Yousef Usama, Raya Yasser, Abdel-Ghani Mohamed M, El-Gohari Hayam, Atwa Samar A

机构信息

Department of Psychiatry, Faculty of Medicine, Zagazig University , Egypt.

出版信息

Am J Drug Alcohol Abuse. 2015 May;41(3):206-11. doi: 10.3109/00952990.2015.1014959. Epub 2015 Apr 10.

Abstract

BACKGROUND

Tramadol abuse liability is underestimated and the evidence of abuse and dependence is emerging. It has many health and social consequences especially in adolescents. Tramadol abuse has not been well studied in Egypt. The aim of this study was to estimate the prevalence and associated correlates of tramadol use and abuse among school students in Egypt.

METHODS

A total of 204 students, aged 13-18 years, from six schools in Zagazig, Egypt, were screened for tramadol use using The Drug Use Disorders Identification Test and a urine screen for tramadol.

RESULTS

The prevalence of tramadol use was 8.8% among school students and the average age at onset of tramadol use was 16.5 ± 1.1. Some 83% of the users were using tramadol alone while the rest (17%) were using a combination of tramadol, alcohol, and cannabis. Two-thirds of these students started with tramadol as the first drug after the onset of tobacco smoking. Over one third of tramadol users had drug-related problems and 6% had dependence. There was a significant association between tramadol use and older age, male gender, and smoking. Drug-related problems were negatively correlated with age at onset of tramadol use.

CONCLUSIONS

Tramadol use was common among adolescents and over one third of tramadol users had drug-related problems. Population-based longitudinal studies are needed to investigate tramadol use and the possible role of tramadol as a gateway drug in the development of substance abuse in Egypt.

摘要

背景

曲马多的滥用倾向被低估,且有关其滥用和成瘾的证据不断涌现。它会引发诸多健康和社会问题,尤其是在青少年中。在埃及,曲马多滥用尚未得到充分研究。本研究旨在评估埃及在校学生中曲马多使用及滥用的流行率及其相关因素。

方法

对来自埃及扎加齐格六所学校的204名年龄在13至18岁的学生进行筛查,使用药物使用障碍识别测试及曲马多尿液筛查来检测曲马多使用情况。

结果

在校学生中曲马多使用率为8.8%,曲马多开始使用的平均年龄为16.5±1.1岁。约83%的使用者单独使用曲马多,其余17%同时使用曲马多、酒精和大麻。这些学生中有三分之二在开始吸烟后将曲马多作为第一种使用的毒品。超过三分之一的曲马多使用者存在与毒品相关的问题,6%的人有成瘾问题。曲马多使用与年龄较大、男性性别及吸烟之间存在显著关联。与毒品相关的问题与曲马多开始使用的年龄呈负相关。

结论

曲马多使用在青少年中很常见,超过三分之一的曲马多使用者存在与毒品相关的问题。需要开展基于人群的纵向研究,以调查埃及曲马多的使用情况以及曲马多作为入门毒品在药物滥用发展过程中可能发挥的作用。

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