Bertram B, Wolf S, Hof A, Jung F, Reim M
Abt. Augenheikunde der Med. Fak. der RWTH Aachen.
Klin Monbl Augenheilkd. 1989 Oct;195(4):254-6. doi: 10.1055/s-2008-1046451.
In a retrospective analysis of findings in 12 patients with Eales' disease significant changes in blood fluidity were established. The six female and six male patients, aged between 15 and 59, were examined in the acute and subclinical stages and when a recurrence occurred. The rheologic parameters plasma viscosity, erythrocyte rigidity, and erythrocyte aggregation were significantly increased in the acute stage and when there was a recurrence, while in the subclinical stage the rheologic values improved to normal. No correlation could be found between the severity of the clinical picture in the various phases and the rheologic values. None of the other biochemical, microbiologic, and immunologic parameters were pathologic in any stage of the disease. In particular, virus serology, protein, immune, and hemoglobin electrophoresis were normal in all patients. While the etiology of Eales' disease remains unknown, deteroration in erythrocyte rigidity appears to play a part in the pathophysiology of the disease.
在一项对12例伊尔斯病患者检查结果的回顾性分析中，发现血液流动性有显著变化。6名女性和6名男性患者，年龄在15至59岁之间，在急性期、亚临床期以及复发时接受了检查。在急性期和复发时，流变学参数血浆粘度、红细胞刚性和红细胞聚集显著增加，而在亚临床期，流变学值恢复正常。在疾病的各个阶段，临床表现的严重程度与流变学值之间未发现相关性。在疾病的任何阶段，其他生化、微生物学和免疫学参数均无病理性变化。特别是，所有患者的病毒血清学、蛋白质、免疫和血红蛋白电泳均正常。虽然伊尔斯病的病因仍然不明，但红细胞刚性的恶化似乎在该疾病的病理生理学中起作用。
