Sokhin A A, Monogarova N E, Zeligman V S, Chernykh S N, Radugina G S
Klin Med (Mosk). 1989 Sep;67(9):38-41.
Follow-up of 114 patients with bronchiectasis has demonstrated that immunomodulation agents levamisole and splenin included in combined treatment augment their therapeutic effect and normalize the immune status of patients. This is manifested by normalization of the amount and functional activity to T-lymphocytes, the content of IgG, IgM and IgA and the autoimmune shifts. A favourable effect was encountered significantly more often than that in patient who were treated by the traditional methods without the use of the immunomodulation agents and in those who were given only levamisole and splenin together with anti-bacterial and hygienic therapy.
对114例支气管扩张症患者的随访表明，联合治疗中使用的免疫调节剂左旋咪唑和脾宁可增强治疗效果，并使患者的免疫状态恢复正常。这表现为T淋巴细胞数量和功能活性、IgG、IgM和IgA含量以及自身免疫变化的正常化。与未使用免疫调节剂的传统治疗患者以及仅接受左旋咪唑和脾宁联合抗菌及卫生治疗的患者相比，出现良好效果的情况明显更为常见。
