Intellect Dev Disabil. 2015 Apr;53(2):91-9. doi: 10.1352/1934-9556-53.2.91.
This study examined mammogram reports of women with Down syndrome (DS) treated in the largest medical facility specifically serving adults with DS in the United States. Records of 684 women and results of 993 mammograms were reviewed, including 902 screening and 93 diagnostic mammograms. Only 2 (0.7%) women had a diagnosis of breast cancer. This study found a low rate of breast cancer among women with DS, a finding which is consistent with previous studies. The financial cost per finding was high, the benefit of the mammograms questionable, and the potential for harm greater. With less than 1% of the women with DS in this study developing breast cancer, further discussion is recommended to assess whether mammography is a beneficial, cost-effective part of health maintenance for women with DS.
本研究调查了在美国最大的专为唐氏综合征（Down syndrome，DS）成人服务的医疗设施中接受治疗的女性的乳房 X 光检查报告。回顾了 684 名女性的记录和 993 次乳房 X 光检查的结果，包括 902 次筛查和 93 次诊断性乳房 X 光检查。仅有 2 名（0.7%）女性被诊断患有乳腺癌。本研究发现，DS 女性的乳腺癌发病率较低，这一发现与之前的研究一致。发现乳腺癌的经济成本很高，乳房 X 光检查的益处值得怀疑，潜在的危害更大。在本研究中，只有不到 1%的 DS 女性患有乳腺癌，因此建议进一步讨论，以评估乳房 X 光检查是否是 DS 女性维持健康的有益且具有成本效益的一部分。
