Department of Bionanoscience, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, the Netherlands; Kavli Institute of Nanoscience, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, the Netherlands.
Department of Bionanoscience, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, the Netherlands; Kavli Institute of Nanoscience, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, the Netherlands.
Cell. 2015 Apr 9;161(2):195-6. doi: 10.1016/j.cell.2015.03.039.
How do cells collectively control an organ's behavior? By plucking various numbers of hairs from the mouse skin, Chen et al. show that hairs regenerate only when a sufficiently high density of them are plucked. Remarkably, a hair follicle can only regenerate in concert with other follicles, but not autonomously.
细胞如何集体控制器官的行为?陈等通过从老鼠皮肤中拔出不同数量的毛发,发现只有当拔出足够数量的毛发时,毛发才会再生。值得注意的是,一个毛囊只能与其他毛囊协同再生,而不能自主再生。