Nakahira Mitsuhiko, Nakatani Hiroaki
Department of Head and Neck Surgery, Saitama Medical University International Medical Center, 1397-1 Yamane, Hidaka, Saitama 350-1298, Japan.
Department of Otolaryngology, National Hospital Organization Fukuyama Medical Center, 4-14-17 Okinogamicho, Fukuyama, Hiroshima 720-0825, Japan.
Case Rep Otolaryngol. 2015;2015:326251. doi: 10.1155/2015/326251. Epub 2015 Mar 12.
Although a thyroglossal duct cyst is a congenital anomaly, it can also appear in adults. Despite the presence of embryological remnants, it is still unclear why the cyst should suddenly develop later in life. We report a case of a 46-year-old male with an extravasation mucocele arising from a long-standing lingual thyroglossal duct remnant. MRI demonstrated a lingual cystic lesion near the hyoid bone associated with a suprahyoid tract-like structure masquerading as a thyroglossal duct cyst. However, histopathological examination demonstrated a mucocele secondary to a rupture of a thyroglossal duct remnant with numerous intramural heterotopic salivary glands. We propose a new mechanism of an acquired cystic formation of this congenital disease that excessive production of mucus from heterotopic salivary glands and a physical trauma such as swallowing may lead to extravasation of mucus from the thyroglossal duct.
虽然甲状舌管囊肿是一种先天性异常，但也可出现在成年人中。尽管存在胚胎残余物，但囊肿为何会在生命后期突然出现仍不清楚。我们报告一例46岁男性病例，其长期存在的舌部甲状舌管残余物引发了黏液外渗性黏液囊肿。磁共振成像（MRI）显示舌骨附近有一个舌部囊性病变，伴有一个类似舌骨上管道样结构，伪装成甲状舌管囊肿。然而，组织病理学检查显示，这是一个甲状舌管残余物破裂继发的黏液囊肿，伴有大量壁内异位唾液腺。我们提出了一种关于这种先天性疾病后天性囊性形成的新机制，即异位唾液腺过度分泌黏液以及诸如吞咽等物理创伤可能导致黏液从甲状舌管外渗。
