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[前庭神经鞘瘤:10年67例手术治疗]

[Vestibular schwannomas: Surgical treatment of 67 cases in 10 years].

作者信息

Mura Jorge, Cuevas José Luis, Rojas-Zalazar David, Riquelme Francisco, Luna Felipe, Sariego Homero, Marengo Juan José

机构信息

Instituto de Neurocirugía Asenjo, Santiago de Chile, Chile; Departamento de Ciencias Neurológicas Sede Oriente, Universidad de Chile, Santiago de Chile, Chile.

Instituto de Neurocirugía Asenjo, Santiago de Chile, Chile; Departamento de Ciencias Neurológicas Sede Oriente, Universidad de Chile, Santiago de Chile, Chile; Servicio de Neurocirugía, Hospital de Puerto Montt , Puerto Montt, Chile.

出版信息

Neurocirugia (Astur). 2015 Nov-Dec;26(6):261-7. doi: 10.1016/j.neucir.2015.02.005. Epub 2015 Apr 7.

DOI:10.1016/j.neucir.2015.02.005
PMID:25861897
Abstract

INTRODUCTION

Vestibular Schwannomas (VS) are benign intracranial tumors, for which their current management is a matter of debate, although microsurgical treatment remains the mode of choice in the majority of cases.

OBJECTIVE

To describe the surgical outcome of patients operated on for a VS in a Chilean Public Hospital.

MATERIAL AND METHOD

A series of 67 patients treated surgically between 2002 and 2012, in the Institute of Neurosurgery Asenjo is presented.

RESULTS

Sixty-five cases (97%) corresponded to Koos III and IV tumors, of which 52% were large (3-4 cm) or Giant (>4 cm). Forty-one cases were operated on using a retrosigmoid transmeatalapproach (61%). Total resection was achieved in 97% of the cases and subtotal in the remaining 3%. A mean six months follow-up showed that good facial function (House-Brackmann I or II) was obtained in 32.7% of the patients, and moderate function (House-Brackmann III or IV) in 42.3%. Cardiopulmonary complications were the most frequent (28%), and mortality was 1.5%.

CONCLUSIONS

The VS are tumors that can cause significant neurological deficit in advanced stages, despite their benign nature. Surgical treatment is very complex, and must be performed by specialized teams to ensure optimal functional results.

摘要

引言

前庭神经鞘瘤(VS)是良性颅内肿瘤,尽管显微外科治疗在大多数情况下仍是首选治疗方式,但目前其治疗方法仍存在争议。

目的

描述在智利一家公立医院接受VS手术治疗的患者的手术结果。

材料与方法

介绍了2002年至2012年间在阿森霍神经外科研究所接受手术治疗的67例患者。

结果

65例(97%)为库斯III级和IV级肿瘤,其中52%为大型(3 - 4厘米)或巨大型(>4厘米)。41例采用乙状窦后经耳道入路进行手术(61%)。97%的病例实现了全切,其余3%为次全切。平均六个月的随访显示,32.7%的患者获得了良好的面部功能(House-Brackmann I级或II级),42.3%的患者获得了中等功能(House-Brackmann III级或IV级)。心肺并发症最为常见(28%),死亡率为1.5%。

结论

VS是一种肿瘤,尽管其性质为良性,但在晚期可导致严重的神经功能缺损。手术治疗非常复杂,必须由专业团队进行以确保最佳的功能结果。

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