Raczyńska A
Med Dosw Mikrobiol. 1989;41(2):73-80.
Two hundred ninety two staphylococcal strains were isolated out of 130 saliva samples taken from children and adults, among which 116 were coagulase-positive and 176 coagulase negative. Bacteriocinogenic activity against Staphylococcus aureus strain Oxford 209P was found in 13 (4.5%) of the strains only. On the other hand, when a set of 15 sensitive staphylococcal strains selected by cross checking was used for the study 260 (89.0%) strains were found to be bacteriocinogenic. It was found that a higher percentage of coagulase-positive staphylococcal strains is sensitive to staphylococcins than of coagulase-negative strains. However, mean zone of inhibition is smaller in the case of former than of the latter strains. It was shown, that in the case of active strains a positive correlation exists between a percentage of coagulase-positive and negative strains inhibited by them and also between a percentage of all inhibited strains and a mean diameter if the growth inhibition zone. Simultaneous occurrence in saliva of two or more staphylococcal strains was found in 106 persons examined. In 93.4% of those cases coexisting strains did not show antagonistic properties: in remaining 6.6% despite of the number of simultaneously existing strains in oral cavity only one strain showed antagonistic properties against the remaining strains.
从儿童和成人的130份唾液样本中分离出292株葡萄球菌菌株，其中116株凝固酶阳性，176株凝固酶阴性。仅在13株（4.5%）菌株中发现了对金黄色葡萄球菌牛津209P菌株的产细菌素活性。另一方面，当使用通过交叉检查挑选出的一组15株敏感葡萄球菌菌株进行研究时，发现260株（89.0%）菌株具有产细菌素能力。结果发现，凝固酶阳性葡萄球菌菌株对葡萄球菌素的敏感性高于凝固酶阴性菌株。然而，前者的平均抑菌圈比后者小。结果表明，对于有活性的菌株，其抑制的凝固酶阳性和阴性菌株的百分比之间，以及所有被抑制菌株的百分比与生长抑制圈的平均直径之间均存在正相关。在接受检查的106人中，发现唾液中同时存在两种或更多葡萄球菌菌株。在93.4%的此类病例中，共存菌株未表现出拮抗特性：在其余6.6%的病例中，尽管口腔中同时存在多种菌株，但只有一株对其余菌株表现出拮抗特性。
