Gunda Sampath, Kanmanthareddy Arun, Atkins Donita, Bommana Sudharani, Pimentel Rhea, Drisko Jeanne, Dibiase Luigi, Beheiry Salwa, Hao Steven, Natale Andrea, Lakkireddy Dhanunjaya
Division of Cardiology, University of Kansas Hospital and Medical Center, Kansas City, KS, 66160, USA.
J Interv Card Electrophysiol. 2015 Aug;43(2):105-10. doi: 10.1007/s10840-015-9996-1. Epub 2015 Apr 12.
Neurocardiogenic syncope (NCS) is a common clinical condition characterized by abrupt cardiovascular autonomic changes resulting in syncope. This is a recurring condition with mixed results from current strategies of treatment.
Subjects with a diagnosis of NCS were screened and enrolled. All the participants were given a DVD containing yoga videos and were instructed to practice yoga therapy for 60 min, three times a week for 3 consecutive months. Syncope functional status questionnaire score (SFSQS) was administered at the beginning and the end of the study. The subjects were followed for 3 months and underwent repeat tilt table testing at the end of the study.
Of the 60 patients screened, 44 subjects were enrolled, 21 in the intervention group and 23 in the control group. Most of the participants were females, and the mean age was 21 ± 3 years. In the intervention group, who finished the yoga regimen, there was a statistically significant improvement from control phase to the intervention phase, in number of episodes of syncope (4 ± 1 vs 1.3 ± 0.7, p < 0.001) and presyncope (4.7 ± 1.5 vs 1.5 ± 0.5, p < 0.001). The mean SFSQS also decreased from 67 ± 7.8 to 29.8 ± 4.6 (p < 0.001). All subjects had positive head up tilt table (HUTT) study at the time of enrollment compared to only six patients at the completion of intervention phase (10/100 vs 6/28 %, p < 0.0001).
Yoga therapy can potentially improve the symptoms of presyncope and syncope in young female patients with NCS.
神经心源性晕厥（NCS）是一种常见的临床病症，其特征为心血管自主神经突然发生变化，进而导致晕厥。这是一种复发性病症，当前的治疗策略效果不一。
对诊断为NCS的受试者进行筛查并纳入研究。所有参与者均收到一张包含瑜伽视频的DVD，并被指导每周进行3次、每次60分钟的瑜伽疗法练习，持续3个月。在研究开始和结束时进行晕厥功能状态问卷评分（SFSQS）。对受试者进行3个月的随访，并在研究结束时进行重复倾斜试验。
在筛查的60例患者中，44例受试者被纳入研究，干预组有21例，对照组有23例。大多数参与者为女性，平均年龄为21±3岁。在完成瑜伽疗程的干预组中，从对照阶段到干预阶段，晕厥发作次数（4±1对1.3±0.7，p<0.001）和晕厥前症状发作次数（4.7±1.5对1.5±0.5，p<0.001）有统计学意义上的显著改善。SFSQS的平均分也从67±7.8降至29.8±4.6（p<0.001）。与干预阶段结束时仅6例患者相比，所有受试者在入组时直立倾斜试验（HUTT）结果均为阳性（10/100对6/28%，p<0.0001）。
瑜伽疗法可能改善年轻女性NCS患者的晕厥前症状和晕厥症状。
