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[Characteristics of a frequently repetitive sequence family in the bull genome].

作者信息

Akopian K Zh, Gening L V, Begetova T V, Tarantul V Z, Gazarian K G

出版信息

Mol Biol (Mosk). 1989 Jul-Aug;23(4):988-95.

PMID:2586512
Abstract

The repeated sequences situated in 5'- and 3'-flanking regions of the bovine growth hormone gene were cloned and characterized. It was shown that they are related to a described before PstI-family of bovine repeats with a frequency of repetition about 10(5). PstI-repeats are found only in genomes of sheep and goats subfamily (Carpinae) and not found in DNA of other analysed vertebrate species. Repeats of this family are situated in the genome as a number of dispersed clusters, they have conservative structure and are alike by the frequency of repetition in the DNA of all organisms that contain them. The presence of sequences homologous to PstI-repeats are shown in bovine pituitary poly(A)+ cytoplasmic RNA by means of North-hybridization.

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