居住在工业园区附近的52名韩国女性的姐妹染色单体交换情况。

Sister-chromatid exchanges in 52 Korean women living in the vicinity of an industrial complex.

作者信息

Shim J S, Lee H K, Kim Y H, Roh J K, Anderson D

机构信息

Toxicology Center, Korea Research Institute of Chemical Technology, Daejeon City.

出版信息

Mutat Res. 1989 Dec;224(4):511-5. doi: 10.1016/0165-1218(89)90078-5.

DOI:10.1016/0165-1218(89)90078-5

PMID:2586547

Abstract

Sister-chromatid exchanges (SCE) were examined in the peripheral lymphocytes of 52 Korean women living in the vicinity of an industrial complex. They were generally non-smokers ranging from 22 to 56 years of age. The mean SCE score of the volunteers was 6.01 +/- 0.15 (SE). Only coffee intake produced a significant increase of SCE by comparison with the mean SCE for those that did not take coffee. Other parameters, including alcohol intake, working in industry and the presence of hepatitis B surface antigen (HBsAg), did not produce an increase in SCE. There was no effect on SCE due to age.

摘要

对居住在工业园区附近的52名韩国女性外周淋巴细胞中的姐妹染色单体交换（SCE）进行了检测。她们一般不吸烟，年龄在22岁至56岁之间。志愿者的平均SCE分数为6.01±0.15（标准误）。与不喝咖啡的人相比，仅咖啡摄入量会使SCE显著增加。其他参数，包括酒精摄入量、在工业领域工作以及乙肝表面抗原（HBsAg）的存在，均未导致SCE增加。年龄对SCE没有影响。