copeptin在急性卒中患者中的预后价值
Prognostic value of copeptin in patients with acute stroke.
作者信息
Jiao Lidong, Chu Changbiao, Zhou Shijie
机构信息
Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
出版信息
Expert Rev Neurother. 2015 May;15(5):563-70. doi: 10.1586/14737175.2015.1030734. Epub 2015 Apr 12.
CONTEXT
There is a need to improve stroke care through the prompt identification of stroke patients at increased risk of an adverse outcome.
OBJECTIVE
To evaluate the prognostic value of copeptin in patients with stroke.
METHODS
We systematically searched PubMed and Embase for relevant studies. Poor outcome and mortality were analyzed.
RESULTS
Twelve studies, containing 2682 patients, were included. Pooled analysis showed that copeptin is an independent prognostic marker of poor outcome after acute stroke and there is a borderline effect of copeptin in predicting mortality after acute stroke.
CONCLUSIONS
Copeptin is an independent predictor of poor outcome and mortality for patients with acute stroke.
背景
需要通过及时识别不良结局风险增加的中风患者来改善中风护理。
目的
评估 copeptin 在中风患者中的预后价值。
方法
我们系统检索了 PubMed 和 Embase 以查找相关研究。对不良结局和死亡率进行了分析。
结果
纳入了 12 项研究，共 2682 名患者。汇总分析表明，copeptin 是急性中风后不良结局的独立预后标志物，且 copeptin 在预测急性中风后死亡率方面有临界效应。
结论
copeptin 是急性中风患者不良结局和死亡率的独立预测因子。
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