BCNatal, Barcelona Center for Maternal-Fetal Medicine and Neonatology, Hospital Clínic and Hospital Sant Joan de Déu, IDIBAPS, University of Barcelona, and Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER) - Maternal-Fetal Medicine and Neonatology, Barcelona, Spain.
Department of Pediatric Surgery, Hospital Sant Joan de Déu, Barcelona, Spain.
Ultrasound Obstet Gynecol. 2015 Nov;46(5):623-6. doi: 10.1002/uog.14876. Epub 2015 Oct 12.
We report on the successful use of fetoscopic surgery to treat a case of prolapsed ureterocele in a female fetus. At 21 weeks' gestation, a double renal system with an intravesical ureterocele obstructing the bladder outlet was diagnosed, causing severe megacystis, bilateral hydronephrosis and progressive oligohydramnios. Ultrasound evaluation following referral to our center confirmed severe bilateral hydronephrosis with pelvic and calyceal dilatation, but amniotic fluid volume was normal and the ureterocele was not visualized in the bladder. Instead, a cystic mass within the external genitalia was observed, suggestive of a prolapsed ureterocele, causing intermittently severe obstruction of the urethra. The parents were counseled about the uncertain prognosis and fetal surgery to decompress the urinary system was proposed. The procedure involved firing a contact diode laser until perforation of the ureterocele was achieved. Following laser surgery, resolution of megacystis, reduction of hydronephrosis and normalization of amniotic fluid volume were observed. Our report demonstrates that fetoscopic decompression of a distal urethral obstruction is feasible in the rare event of congenital prolapsed ureterocele.
我们报告了一例成功使用胎儿镜手术治疗女性胎儿输尿管膨出的病例。在 21 周妊娠时,诊断出双肾系统伴有膀胱出口处的腔内输尿管膨出,导致严重的巨膀胱、双侧肾积水和进行性羊水过少。转诊至我们中心后进行的超声评估证实了严重的双侧肾积水,伴有骨盆和肾盏扩张,但羊水体积正常,膀胱内未观察到输尿管膨出。相反,在外生殖器内观察到一个囊性肿块,提示输尿管膨出脱垂,间歇性严重尿道梗阻。向父母告知了不确定的预后,并提出了胎儿手术来解除泌尿系统的压力。该手术包括发射接触二极管激光,直到输尿管膨出穿孔。激光手术后,巨膀胱得到缓解,肾积水减少,羊水体积恢复正常。我们的报告表明,在罕见的先天性输尿管膨出脱垂的情况下,远端尿道梗阻的胎儿镜减压是可行的。