单侧与双侧眼眶IgG4相关性疾病临床特征的对比研究
[Comparative study of clinical features between unilateral and bilateral orbital IgG4-related disease].
作者信息
Coloma-González I, Ceriotto A, Flores-Preciado J, Corredor-Casas S, Salcedo-Casillas G
机构信息
Servicio de Órbita, Párpados y Vía Lagrimal, Hospital Dr. Luis Sánchez Bulnes, Asociación para Evitar la Ceguera IAP, México D.F. México.
Servicio de Órbita, Párpados y Vía Lagrimal, Hospital Dr. Luis Sánchez Bulnes, Asociación para Evitar la Ceguera IAP, México D.F. México.
出版信息
Arch Soc Esp Oftalmol. 2015 Sep;90(9):407-13. doi: 10.1016/j.oftal.2015.02.018. Epub 2015 Apr 10.
OBJECTIVE
Descriptive and comparative study of patients with orbital IgG4-related disease.
MATERIAL AND METHODS
A review and analysis of the cases diagnosed with inflammatory orbital lesion related to IgG4 by the Ophthalmic Pathology Service in the Dr. Luis Sánchez Bulnes Hospital.
RESULTS
A total of 9 cases were found, in which 66% were women, and with a mean age of 48 years and time to diagnosis of 2 years. Unilateral involvement was observed in 56% of cases. All the females experienced pain, and there was an optimal response to corticosteroid treatment in 100% of patients who required medical treatment (one case showed spontaneous resolution). In bilateral cases (44%), only 25% were female, and none had pain as a presenting symptom. Furthermore, 25% of these patients required a combination with immunosuppressants to control inflammation.
CONCLUSIONS
Clinical presentation of patients with unilateral orbital IgG4-related disease differs from those with bilateral involvement.
目的
对眼眶IgG4相关疾病患者进行描述性和对比性研究。
材料与方法
回顾并分析路易斯·桑切斯·布尔内斯博士医院眼科病理科诊断的与IgG4相关的炎性眼眶病变病例。
结果
共发现9例病例，其中66%为女性，平均年龄48岁，诊断时间为2年。56%的病例为单侧受累。所有女性均有疼痛症状，100%需要药物治疗的患者对皮质类固醇治疗反应良好（1例自行缓解）。在双侧病例（44%）中，仅25%为女性，且均无疼痛作为首发症状。此外，这些患者中有25%需要联合使用免疫抑制剂来控制炎症。
结论
单侧眼眶IgG4相关疾病患者的临床表现与双侧受累患者不同。
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