School of Chemical & Biomolecular Engineering, Georgia Institute of Technology, 311 Ferst Drive NW, Atlanta, GA 30332 (USA).
Department of Chemistry, Emory University (USA).
Angew Chem Int Ed Engl. 2015 May 26;54(22):6470-4. doi: 10.1002/anie.201500841. Epub 2015 Apr 13.
Flexible composite polymer/oxide hollow fibers are used as flow reactors for heterogeneously catalyzed reactions in organic synthesis. The fiber synthesis allows for a variety of supported catalysts to be embedded in the walls of the fibers, thus leading to a diverse set of reactions that can be catalyzed in flow. Additionally, the fiber synthesis is scalable (e.g. several reactor beds containing many fibers in a module may be used) and thus they could potentially be used for the large-scale production of organic compounds. Incorporating heterogeneous catalysts in the walls of the fibers presents an alternative to a traditional packed-bed reactor and avoids large pressure drops, which is a crucial challenge when employing microreactors.
柔性复合聚合物/氧化物中空纤维可用作有机合成中多相催化反应的流动反应器。纤维合成可以将各种负载型催化剂嵌入纤维壁中,从而可以在流动相中催化多种不同的反应。此外,纤维合成具有可扩展性(例如,在一个模块中可以使用多个包含许多纤维的反应器床),因此它们有可能用于有机化合物的大规模生产。将多相催化剂纳入纤维壁中为传统的填充床反应器提供了一种替代方案,并避免了大的压降,这是使用微反应器时的一个关键挑战。