Garg S, Appannanavar S B, Mohan B, Taneja N
Department of Medical Microbiology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Indian J Med Microbiol. 2015 Apr-Jun;33(2):311-3. doi: 10.4103/0255-0857.154894.
Chryseobacterium spp are widely distributed in nature but data of their isolation from clinical samples is scanty. Here, we report the first case of AmpC producing C. gleum causing pyonephrosis in a patient having bilateral nephrolithiasis on double J (DJ) stent. The present isolate was resistant to vancomycin, erythromycin, clindamycin, carbapenems and ciprofloxacin and susceptible to tetracycline and minocycline. The patient was treated with tetracycline and recovered without the need for removal of the DJ stent. The environmental surveillance carried out to trace the nosocomial origin of the isolate was negative. Since antimicrobial susceptibility of this isolate is different from previous reports, we emphasise that in vitro susceptibility testing should be sought to choose optimal antimicrobial agents for these Nonfermentative Gram-Negative Bacilli (NFGNBs) with different susceptibility patterns.
金黄杆菌属广泛分布于自然界，但从临床样本中分离出该菌的数据却很少。在此，我们报告首例产AmpC酶的黏金黄杆菌导致一名双侧肾结石且植入双J（DJ）支架的患者发生肾积脓的病例。目前分离出的菌株对万古霉素、红霉素、克林霉素、碳青霉烯类和环丙沙星耐药，对四环素和米诺环素敏感。该患者接受四环素治疗后康复，无需取出DJ支架。为追踪该分离株的医院感染源而进行的环境监测结果为阴性。由于该分离株的抗菌药敏情况与之前的报告不同，我们强调对于这些药敏模式不同的非发酵革兰阴性杆菌（NFGNBs），应进行体外药敏试验以选择最佳抗菌药物。
