Angrup Archana, Sharma Bhawna, Sehgal Inderpaul Singh, Biswal Manisha, Ray Pallab
Department of Medical Microbiology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Department of Pulmonary Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
J Lab Physicians. 2022 Oct 26;15(1):97-105. doi: 10.1055/s-0042-1757412. eCollection 2023 Mar.
In the ongoing severe acute respiratory syndrome coronavirus 2 pandemic, a long hospital stay and empirical broad-spectrum antibiotics make the patients prone to acquire nosocomial infections especially with unconventional organisms, and is one such rare nosocomial pathogen. The given study is a case-series-based study conducted from September 2020 to April 2021 in which clinically suspected pneumonia patients who recovered from coronavirus disease 2019 (COVID-19) were included. Seventeen isolates were obtained in pure culture from the tracheal aspirates of nine COVID-19 patients (including repeat samples to rule out colonization) within a period of eight months (September 2020-April 2021). Our records showed that there has been an increase in the number of isolates of obtained in respiratory samples in 2020. We also did a review of literature of all the cases of pneumonia reported till now. To the best of our knowledge, this is the first study reporting the isolation of this rare pathogen from COVID-19 patients with clinical significance in a large cohort of patients. Therefore, it becomes important to consider this pathogen as a significant cause of respiratory infections, especially in patients recovered post COVID-19.
在持续的新型冠状病毒2型大流行中，长时间住院和经验性使用广谱抗生素使患者容易获得医院感染，尤其是感染非常规病原体，而[病原体名称未给出]就是这样一种罕见的医院病原体。
给定的研究是一项基于病例系列的研究，于2020年9月至2021年4月进行，纳入了从2019冠状病毒病（COVID-19）康复的临床疑似肺炎患者。
在八个月（2020年9月至2021年4月）期间，从9名COVID-19患者的气管吸出物中获得了17株纯培养分离株（包括重复样本以排除定植）。我们的记录显示，2020年呼吸道样本中[病原体名称未给出]分离株的数量有所增加。我们还对迄今为止报道的所有[病原体名称未给出]肺炎病例的文献进行了综述。
据我们所知，这是第一项在大量患者队列中报告从具有临床意义的COVID-19患者中分离出这种罕见病原体的研究。因此，将这种病原体视为呼吸道感染的重要原因变得很重要，尤其是在COVID-19康复后的患者中。
