Nyasulu Peter, Mogoere Serame, Umanah Teye, Setswe Geoffrey
School of Health Sciences, Monash University, 144 Peter Road, Ruimsig, Johannesburg 1794, South Africa ; School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, 7 York Road, Park Town, Johannesburg 2193, South Africa.
School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, 7 York Road, Park Town, Johannesburg 2193, South Africa.
Tuberc Res Treat. 2015;2015:752709. doi: 10.1155/2015/752709. Epub 2015 Mar 17.
Introduction. Correctional facilities house large number of inmates who are at high risk of developing tuberculosis (TB); however factors associated with TB among inmates at Mangaung Correctional Centre have not been studied. Study Population and Methods. We undertook a case control study and reviewed a total of 1140 medical records of inmates treated for TB between 2009 and 2010. Cases were selected randomly from the medical records of inmates who were treated. Data collected were analysed using STATA version 12.0 and determinants of TB were evaluated using multiple logistic regression analyses. Factors with P < 0.05 were considered significant. Results. Prevalence of TB was 8.8% and 52% of inmates with TB were aged 31-40 years; 58% of the TB cases were HIV positive and 34% of them had CD4 cell count 350 cells/mm(3). Factors associated with TB among inmates were HIV coinfection (OR: 4.2; 95% CI: 2.64-7.00); previous history of TB disease (OR: 3.58; 95% CI: 2.25-5.70); and smoking (OR: 2.1; 95% CI: 1.16-3.81). Conclusion. Interventions to improve TB detection such as regular screening of inmates with such factors need to be reinforced to control transmission of TB among inmates and the community.
引言。惩教设施关押着大量有患结核病(TB)高风险的囚犯;然而,尚未对曼加昂惩教中心囚犯中与结核病相关的因素进行研究。研究人群与方法。我们开展了一项病例对照研究,并回顾了2009年至2010年间接受结核病治疗的1140名囚犯的医疗记录。病例从接受治疗的囚犯医疗记录中随机选取。收集的数据使用STATA 12.0版本进行分析,结核病的决定因素使用多元逻辑回归分析进行评估。P<0.05的因素被认为具有显著性。结果。结核病患病率为8.8%,52%的结核病囚犯年龄在31 - 40岁;58%的结核病病例HIV呈阳性,其中34%的CD4细胞计数<350个细胞/mm³。囚犯中与结核病相关的因素有HIV合并感染(比值比:4.2;95%置信区间:2.64 - 7.00);既往结核病病史(比值比:3.58;95%置信区间:2.25 - 5.70);以及吸烟(比值比:2.1;95%置信区间:1.16 - 3.81)。结论。需要加强干预措施以改善结核病检测,如对有此类因素的囚犯进行定期筛查,以控制结核病在囚犯和社区中的传播。