Sarkhy Ahmed Al, El Mouzan Mohammad I, Saeed Elshazaly, Alanazi Aziz, Alghamdi Sharifa, Anil Shirin, Assiri Asaad
Division of Gastroenterology, Department of Pediatrics, King Khalid University Hospital, King Saud University, Saudi Arabia. ; Prince Abdullah Bin Khalid Celiac Disease Research Chair, King Saud University, Saudi Arabia.
Prince Abdullah Bin Khalid Celiac Disease Research Chair, King Saud University, Saudi Arabia.
Pediatr Gastroenterol Hepatol Nutr. 2015 Mar;18(1):23-9. doi: 10.5223/pghn.2015.18.1.23. Epub 2015 Mar 30.
To describe the clinical characteristics of celiac disease (CD) among Saudi children and to determine the adherence rate to gluten free diet (GFD) and its determinant factors among them.
A cross-sectional study was conducted, in which all the families registered in the Saudi Celiac Patients Support Group were sent an online survey. Only families with children 18 years of age and younger with biopsy-confirmed CD were included.
The median age of the 113 included children was 9.9 years, the median age at symptom onset was 5.5 years and the median age at diagnosis was 7 years, the median time between the presentation and the final diagnosis was 1 year. Sixty two of the involved children were females. Ninety two percent of the patients were symptomatic at the diagnosis while eight percent were asymptomatic. The commonest presenting symptoms included: chronic abdominal pain (59.3%), poor weight gain (54%), abdominal distention, gases, bloating (46.1%) and chronic diarrhea (41.6%). Sixty percent of the involved children were reported to be strictly adherent to GFD. Younger age at diagnosis and shorter duration since the diagnosis were associated with a better adherence rate.
CD has similar clinical presentations among Saudi children compared to other parts of the ward; however, the adherence to GFD is relatively poor. Younger age at diagnosis and shorter duration since the diagnosis were associated with a better adherence rate.
描述沙特儿童乳糜泻(CD)的临床特征,并确定他们对无麸质饮食(GFD)的依从率及其决定因素。
进行了一项横断面研究,向沙特乳糜泻患者支持小组登记的所有家庭发送了在线调查问卷。仅纳入有18岁及以下经活检确诊为CD的儿童的家庭。
纳入的113名儿童的中位年龄为9.9岁,症状出现的中位年龄为5.5岁,诊断时的中位年龄为7岁,就诊与最终诊断之间的中位时间为1年。其中62名儿童为女性。92%的患者在诊断时有症状,8%无症状。最常见的症状包括:慢性腹痛(59.3%)、体重增加缓慢(54%)、腹胀、嗳气、腹部膨隆(46.1%)和慢性腹泻(41.6%)。据报告,60%的患儿严格遵守GFD饮食。诊断时年龄较小以及诊断后病程较短与较好的依从率相关。
与世界其他地区相比,沙特儿童CD的临床表现相似;然而,对GFD的依从性相对较差。诊断时年龄较小以及诊断后病程较短与较好的依从率相关。