van den Hoek J A, van Haastrecht H J, Fennema J S, Kint J A, van Doornum G J, Coutinho R A
Ned Tijdschr Geneeskd. 1989 Dec 2;133(48):2392-6.
We studied the prevalence of Chlamydia trachomatis (CT) infection as well as its predictors among a sample (1000) of visitors (651 male, 349 female) of a clinic for sexually transmitted diseases (STD) in Amsterdam. The prevalence of CT was higher than that of gonorrhoea: among men, 14.3% and 11.5% and among women, 12.9% and 6.3% respectively. Independent predictors for CT infections were for men: number of leucocytes in discharge or urine, nature of urethral discharge, age and sex behavior, and in women: being warned as source or contact of a STD, age, nature of cervical discharge and bleeding from the cervical ostium after insertion of a swab. As many as 92% of the male and 81% of the female visitors of our STD clinic should be examined for CT if the presence of anyone or more of these predictors is taken as a criterion. Even then, 5% of the CT infections in women would still be missed. Based on our study results, material for the diagnosis of CT will from now on be collected routinely from all female patients of our STD clinic as well as from all males with urethritis. We advocate the expansion in the Netherlands of facilities for laboratory CT detection and its standard inclusion in STD examination.
我们研究了阿姆斯特丹一家性传播疾病(STD)诊所1000名访客(651名男性,349名女性)样本中沙眼衣原体(CT)感染的患病率及其预测因素。CT的患病率高于淋病:男性中分别为14.3%和11.5%,女性中分别为12.9%和6.3%。CT感染的独立预测因素在男性中为:分泌物或尿液中的白细胞数量、尿道分泌物的性质、年龄和性行为;在女性中为:被警告为STD的传染源或接触者、年龄、宫颈分泌物的性质以及插入拭子后宫颈口出血。如果将这些预测因素中的任何一个或多个的存在作为标准,我们STD诊所多达92%的男性访客和81%的女性访客应接受CT检查。即便如此,女性中仍有5%的CT感染会被漏诊。基于我们的研究结果,从现在起,将常规采集我们STD诊所所有女性患者以及所有尿道炎男性患者的CT诊断材料。我们主张在荷兰扩大实验室CT检测设施,并将其标准纳入STD检查。