Kimmel Howard M, Robin Angela L
Louis Stokes Cleveland VA Medical Center, Cleveland, OH;and Case Western Reserve University School of Medicine, Cleveland, OH; email:
Case Western Reserve University School of Medicine, Cleveland, OH.
Wounds. 2013 Sep;25(9):242-50.
This literature review serves to develop an evidence-based algorithm for the treatment of venous ulcerations and the development of a guideline to systemically treat venous leg ulcerations (VLUs) that may improve outcomes, restore function of the affected limb, and reduce health care costs.
The Cochrane Database and PubMed search engine were utilized to accumulate literature concerning venous ulcerations and their treatment. The most relevant literature was reviewed to develop an algorithm to guide treatment of VLUs.
An algorithm was established outlining the use of compression therapy in VLUs present for < 4 weeks. If a wound is present after 4 weeks of therapy and has not reduced in size by ≥ 40%, bilayered living skin equivalents may be indicated.
An algorithm was established to guide the treatment of venous ulcerations. By utilizing a systematic approach in treating VLUs, clinical outcomes may be improved. .
本综述旨在制定一种基于证据的静脉溃疡治疗算法，并制定一套系统性治疗下肢静脉溃疡（VLUs）的指南，以改善治疗效果、恢复患肢功能并降低医疗成本。
利用Cochrane数据库和PubMed搜索引擎收集有关静脉溃疡及其治疗的文献。对最相关的文献进行综述，以制定指导VLUs治疗的算法。
建立了一种算法，概述了对病程小于4周的VLUs使用压迫疗法。如果治疗4周后仍有伤口且伤口大小未缩小≥40%，则可能需要使用双层活性皮肤替代物。
建立了一种指导静脉溃疡治疗的算法。通过采用系统性方法治疗VLUs，可改善临床治疗效果。
