Jobst Vascular Center, Toledo Hospital, Toledo, OH 43606, USA.
J Vasc Surg. 2011 Apr;53(4):1121-9. doi: 10.1016/j.jvs.2010.08.059. Epub 2010 Nov 3.
Venous leg ulcers (VLUs) are a significant health problem that afflicts 1% of the population at some point during their lifetime. Intermittent pneumatic compression (IPC) is widely used to prevent deep venous thrombosis. However, IPC seems to have application to a broader base of circulatory diseases. The intermittent nature of pulsatile external compression produces beneficial physiologic changes, which include hematologic, hemodynamic, and endothelial effects, which should promote healing of VLUs. Clinical studies of the management of VLUs show that IPC increases overall healing and accelerates the rate of healing, leading to current guideline recommendations for care of patients with VLUs. Proper prescription of IPC to improve the management of patients with VLUs requires further definition. It seems that application of IPC in combination with sustained graduated compression improves outcome in patients with the most advanced venous disease.
静脉性腿部溃疡（VLUs）是一个严重的健康问题，影响着人群中的 1%，一生中的某个阶段都会受到影响。间歇性气动压迫（IPC）被广泛用于预防深静脉血栓形成。然而，IPC 似乎适用于更广泛的循环系统疾病基础。脉动外部压迫的间歇性产生有益的生理变化，包括血液学、血液动力学和内皮效应，这应该促进 VLUs 的愈合。VLUs 管理的临床研究表明，IPC 增加了整体愈合率并加速了愈合速度，导致目前针对 VLUs 患者护理的指南建议。为了改善 VLUs 患者的管理，对 IPC 的适当处方需要进一步定义。IPC 与持续分级压缩联合应用似乎可以改善最严重静脉疾病患者的预后。
