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一名美国原住民的人类嗜T淋巴细胞病毒I型相关脊髓病和多发性肌炎

HTLV-I-associated myelopathy and polymyositis in a US native.

作者信息

Evans B K, Gore I, Harrell L E, Arnold T, Oh S J

机构信息

Department of Neurology, University of Alabama Birmingham School of Medicine.

出版信息

Neurology. 1989 Dec;39(12):1572-5. doi: 10.1212/wnl.39.12.1572.

DOI:10.1212/wnl.39.12.1572
PMID:2586771
Abstract

A patient who had always lived in the United States had an HTLV-I infection and a chronic myelopathy clinically mimicking amyotrophic lateral sclerosis. Needle EMG and nerve conduction studies were consistent with anterior horn cell disease but muscle biopsy showed denervation and an inflammatory myopathy. Serum HTLV-I antibody tests were positive and HTLV-I DNA was present in peripheral leukocytes. This is the 1st reported US native with HTLV-I-associated myelopathy and polymyositis.

摘要

一位一直生活在美国的患者感染了人类嗜T淋巴细胞病毒I型(HTLV-I),临床上患有慢性脊髓病,酷似肌萎缩侧索硬化症。针电极肌电图和神经传导研究结果与前角细胞疾病相符,但肌肉活检显示有失神经支配和炎性肌病。血清HTLV-I抗体检测呈阳性,外周血白细胞中存在HTLV-I DNA。这是首例报道的患有HTLV-I相关脊髓病和多发性肌炎的美国本土患者。

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