非黑色素瘤皮肤癌治疗共识：基底细胞癌，包括治疗方法的成本分析。
Consensus for nonmelanoma skin cancer treatment: basal cell carcinoma, including a cost analysis of treatment methods.
作者信息
Kauvar Arielle N B, Cronin Terrence, Roenigk Randall, Hruza George, Bennett Richard
机构信息
*New York Laser & Skin Care, New York, New York; †Department of Dermatology, New York University School of Medicine, New York, New York; ‡Department of Dermatology, University of Miami, Miami, Florida; §Department of Dermatology, Mayo Clinic, Rochester, Minnesota; ‖Laser & Dermatologic Surgery Center, Chesterfield, Missouri; ¶Department of Dermatology, St. Louis University, St. Louis, Missouri; #Department of Dermatology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California; **Department of Dermatology, Keck School of Medicine, University of Southern California, Los Angeles, California.
出版信息
Dermatol Surg. 2015 May;41(5):550-71. doi: 10.1097/DSS.0000000000000296.
BACKGROUND
Basal cell carcinoma (BCC) is the most common cancer in the US population affecting approximately 2.8 million people per year. Basal cell carcinomas are usually slow-growing and rarely metastasize, but they do cause localized tissue destruction, compromised function, and cosmetic disfigurement.
OBJECTIVE
To provide clinicians with guidelines for the management of BCC based on evidence from a comprehensive literature review, and consensus among the authors.
MATERIALS AND METHODS
An extensive review of the medical literature was conducted to evaluate the optimal treatment methods for cutaneous BCC, taking into consideration cure rates, recurrence rates, aesthetic and functional outcomes, and cost-effectiveness of the procedures.
RESULTS
Surgical approaches provide the best outcomes for BCCs. Mohs micrographic surgery provides the highest cure rates while maximizing tissue preservation, maintenance of function, and cosmesis.
CONCLUSION
Mohs micrographic surgery is an efficient and cost-effective procedure and remains the treatment of choice for high-risk BCCs and for those in cosmetically sensitive locations. Nonsurgical modalities may be used for low-risk BCCs when surgery is contraindicated or impractical, but the cure rates are lower.
背景
基底细胞癌（BCC）是美国人群中最常见的癌症，每年影响约280万人。基底细胞癌通常生长缓慢，很少转移，但它们确实会导致局部组织破坏、功能受损和外观损毁。
目的
基于全面文献综述的证据以及作者之间的共识，为临床医生提供基底细胞癌管理指南。
材料与方法
对医学文献进行广泛综述，以评估皮肤基底细胞癌的最佳治疗方法，同时考虑治愈率、复发率、美学和功能结果以及手术的成本效益。
结果
手术方法为基底细胞癌提供了最佳治疗效果。莫氏显微外科手术治愈率最高，同时能最大程度地保留组织、维持功能和美观。
结论
莫氏显微外科手术是一种高效且具成本效益的手术方式，仍然是高危基底细胞癌以及位于对外观敏感部位的基底细胞癌的首选治疗方法。当手术禁忌或不切实际时，非手术方式可用于低危基底细胞癌，但治愈率较低。
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