van der Werken C, Stassen L P, van Vroonhoven J M
Department of Surgery, St.Elisabeth Hospital, Tilburg, The Netherlands.
Neth J Surg. 1989 Oct;41(5):100-3.
Over a 3.5 year period, 550 patients underwent an emergency operation under the diagnosis of acute appendicitis. The appendix proved to be normal in 82 patients, the other 468 patients had signs of acute inflammation with perforation in 142 cases. Management followed a strict protocol with single dose metronidazole as preoperative antibiotic prophylaxis and liberal open wound treatment in case of gross contamination. Consequently, the subcutaneous tissues and the skin were left open in 218 patients. The overall wound infection rate (1.3%) and the intra-abdominal abscess rate (1.1%) were extremely low. Open wound treatment was well accepted by the patients, did not prolong the hospital stay and gave good cosmetic results.
在3.5年的时间里,550例患者因急性阑尾炎诊断接受了急诊手术。结果发现82例患者的阑尾正常,其他468例患者有急性炎症迹象,其中142例发生穿孔。治疗遵循严格的方案,术前使用单剂量甲硝唑作为抗生素预防,在严重污染的情况下采用宽松的开放伤口处理。因此,218例患者的皮下组织和皮肤保持开放。总体伤口感染率(1.3%)和腹腔内脓肿率(1.1%)极低。开放伤口处理得到了患者的良好接受,没有延长住院时间,并且美容效果良好。