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贫血对脑卒中患者功能结局及其脑卒中康复效果的影响。

The Effect of Anemia on the Functional Outcomes of the Stroke Patients and the Efficiency of their Stroke Rehabilitation.

作者信息

Chan Tik, Ganasekaran Ganesh

机构信息

Geriatric and Rehabilitation Department, Internal Medicine Services, The Prince Charles Hospital, Brisbane, Queensland, Australia.

Geriatric and Rehabilitation Department, Internal Medicine Services, The Prince Charles Hospital, Brisbane, Queensland, Australia.

出版信息

J Stroke Cerebrovasc Dis. 2015 Jun;24(6):1438-42. doi: 10.1016/j.jstrokecerebrovasdis.2015.03.009. Epub 2015 Apr 11.

DOI:10.1016/j.jstrokecerebrovasdis.2015.03.009
PMID:25869771
Abstract

BACKGROUND

There has been limited study focusing on the functional outcomes of stroke patients' after rehabilitation, such as functional improvement and discharge destination, length of stay (LOS), and complication rate.

METHODS

A retrospective study was conducted on 123 consecutive patients who were admitted to The Prince Charles Hospital Rehabilitation Unit from January 2011 to December 2012 with clinically defined stroke syndromes. Functional Independence Measure (FIM) score was used to measure the functional improvement. Anemia is defined by using the World Health Organization's criteria (hemoglobin concentration in men <120 mg/dL and in women <110 mg/dL).

RESULTS

During the 2-year period, of the 123 stroke patients, 33 were found to be anemic (26.8%). The demographic factors, baseline admission FIM score, comorbidities, and the types of stroke were all comparable in both anemic and nonanemic groups. It was found that, when selecting only the patients with ischemic stroke for comparison (103 patients), there was a significantly higher FIM score improvement (discharge FIM - admission FIM) in nonanemic group (P = .042). FIM efficiency (FIM change/LOS) was also significantly higher in the nonanemic group (P = .027). Higher percentage of patients were discharged home in nonanemic group (94.3% versus 73.3%, P = .006). In addition, higher rate of complications was found in anemic group (60% versus 39%, P = .049).

CONCLUSIONS

Anemia appears to have a significant effect on the functional improvement and discharge outcomes for patients who had an ischemic stroke. Anemia may also increase the complication rate and affect the efficiency of stroke rehabilitation for those patients.

摘要

背景

针对中风患者康复后的功能结局,如功能改善情况、出院去向、住院时间(LOS)和并发症发生率等的研究有限。

方法

对2011年1月至2012年12月期间连续收治于查尔斯王子医院康复科的123例临床诊断为中风综合征的患者进行回顾性研究。采用功能独立性测量(FIM)评分来衡量功能改善情况。贫血的定义采用世界卫生组织的标准(男性血红蛋白浓度<120mg/dL,女性<110mg/dL)。

结果

在这2年期间,123例中风患者中,有33例被发现贫血(26.8%)。贫血组和非贫血组在人口统计学因素、入院时FIM基线评分、合并症及中风类型方面均具有可比性。结果发现,仅选择缺血性中风患者进行比较时(103例患者),非贫血组的FIM评分改善(出院FIM - 入院FIM)显著更高(P = 0.042)。非贫血组的FIM效率(FIM变化/LOS)也显著更高(P = 0.027)。非贫血组患者出院回家的比例更高(94.3%对73.3%,P = 0.006)。此外,贫血组的并发症发生率更高(60%对39%,P = 0.049)。

结论

贫血似乎对缺血性中风患者的功能改善和出院结局有显著影响。贫血还可能增加并发症发生率,并影响这些患者的中风康复效率。

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