Department of Neurology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, United States.
Department of Neurology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, United States; NewYork-Presbyterian Hospital, Columbia University Irving Medical Center, New York, NY, United States.
Handb Clin Neurol. 2020;172:3-31. doi: 10.1016/B978-0-444-64240-0.00001-5.
Maternal ischemic stroke and cerebral venous sinus thrombosis (CVST) are dreaded complications of pregnancy and major contributors to maternal disability and mortality. This chapter summarizes the incidence and risk factors for maternal arterial ischemic stroke (AIS) and CVST and discusses the pathophysiology of maternal AIS and CVST. The diagnosis, treatment, and secondary preventive strategies for maternal stroke are also reviewed. Special populations at high risk of maternal stroke, including women with moyamoya disease, sickle cell disease, HIV, thrombophilia, and genetic cerebrovascular disorders, are highlighted.
孕产妇脑梗死和脑静脉窦血栓形成（CVST）是妊娠的严重并发症，也是导致孕产妇残疾和死亡的主要原因。本章总结了孕产妇动脉性脑梗死（AIS）和 CVST 的发病率和危险因素，并讨论了孕产妇 AIS 和 CVST 的病理生理学。还回顾了孕产妇脑卒中的诊断、治疗和二级预防策略。重点介绍了一些高危孕产妇人群，包括烟雾病、镰状细胞病、HIV、血栓形成倾向和遗传性脑血管疾病患者。
