Krannig H M, Rohde-Germann H, Straub W
University Eye Hospital, Marburg, FRG.
Ophthalmologica. 1989;199(2-3):100-5. doi: 10.1159/000310024.
A comparative study of Solcoseryl eye drops versus Vitasic eye drops has been carried out under controlled conditions (randomized and double-blind) on a total of 94 patients. 52 had corneal erosion, 30 had dry eye syndrome, 8 cases could not be evaluated. In addition, 2 eyes with photophthalmia were treated with Vitasic and 2 showing keratitis with Solcoseryl. There were no adverse reactions other than 2 instances of stinging with Solcoseryl and 1 case of severe irritation after Vitasic. The patients were examined on days 0, 1, 3 and 7. Results showed a consistent superiority of Solcoseryl eye drops in respect to speed of healing of corneal erosions and moistening of the cornea in the 'dry eye' syndrome which reached statistical significance in some parameters.
在对照条件下(随机双盲),对94例患者开展了素高捷疗眼膏与维他思眼膏的对比研究。其中52例有角膜糜烂,30例有干眼症,8例无法评估。此外,2例电光性眼炎患者用维他思眼膏治疗,2例角膜炎患者用素高捷疗眼膏治疗。除素高捷疗有2例刺痛、维他思有1例严重刺激外,未出现其他不良反应。在第0、1、3和7天对患者进行检查。结果显示,素高捷疗眼膏在角膜糜烂愈合速度和“干眼症”综合征中角膜湿润方面始终具有优势,在某些参数上具有统计学意义。