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Med Arch. 2015 Feb;69(1):60-1. doi: 10.5455/medarh.2015.69.60-61. Epub 2015 Feb 21.
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Melissa officinalis L. - A review of its traditional uses, phytochemistry and pharmacology.香蜂花（Melissa officinalis L.）——传统用途、植物化学与药理学综述
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本文引用的文献

1
Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence.植物药治疗焦虑障碍，第 2 部分：具有支持性临床前证据的临床研究综述。
CNS Drugs. 2013 Apr;27(4):301-19. doi: 10.1007/s40263-013-0059-9.
2
Anxiolytic and antidepressant-like effects of Melissa officinalis (lemon balm) extract in rats: Influence of administration and gender.柠檬香蜂草（柠檬薄荷）提取物对大鼠的抗焦虑和抗抑郁样作用：给药途径和性别影响。
Indian J Pharmacol. 2012 Mar;44(2):189-92. doi: 10.4103/0253-7613.93846.
3
Pilot trial of Melissa officinalis L. leaf extract in the treatment of volunteers suffering from mild-to-moderate anxiety disorders and sleep disturbances.蜜蜂花（Melissa officinalis L.）叶提取物治疗轻至中度焦虑症和睡眠障碍志愿者的初步试验。
Med J Nutrition Metab. 2011 Dec;4(3):211-218. doi: 10.1007/s12349-010-0045-4. Epub 2010 Dec 17.
4
Screening of traditionally used Lebanese herbs for neurological activities.对传统使用的黎巴嫩草药进行神经学活性筛选。
J Ethnopharmacol. 2005 Feb 10;97(1):145-9. doi: 10.1016/j.jep.2004.10.023. Epub 2004 Dec 13.
5
Modulation of mood and cognitive performance following acute administration of single doses of Melissa officinalis (Lemon balm) with human CNS nicotinic and muscarinic receptor-binding properties.单次急性给予具有人中枢神经系统烟碱样和毒蕈碱样受体结合特性的香蜂草（柠檬香脂）后对情绪和认知表现的调节作用。
Neuropsychopharmacology. 2003 Oct;28(10):1871-81. doi: 10.1038/sj.npp.1300230.
6
Aromatherapy as a safe and effective treatment for the management of agitation in severe dementia: the results of a double-blind, placebo-controlled trial with Melissa.芳香疗法作为一种安全有效的治疗方法用于管理重度痴呆患者的激越症状：一项使用香蜂草的双盲、安慰剂对照试验的结果
J Clin Psychiatry. 2002 Jul;63(7):553-8. doi: 10.4088/jcp.v63n0703.
7
Modulation of mood and cognitive performance following acute administration of Melissa officinalis (lemon balm).急性给予香蜂草（柠檬香脂）后对情绪和认知表现的调节作用。
Pharmacol Biochem Behav. 2002 Jul;72(4):953-64. doi: 10.1016/s0091-3057(02)00777-3.
8
A review of herbal medicines for psychiatric disorders.用于精神疾病的草药综述。
Psychiatr Serv. 2000 Sep;51(9):1130-4. doi: 10.1176/appi.ps.51.9.1130.
9
Herbal remedies in psychiatric practice.精神科实践中的草药疗法。
Arch Gen Psychiatry. 1998 Nov;55(11):1033-44. doi: 10.1001/archpsyc.55.11.1033.
10
A method for estimating the probability of adverse drug reactions.一种估算药物不良反应概率的方法。
Clin Pharmacol Ther. 1981 Aug;30(2):239-45. doi: 10.1038/clpt.1981.154.

蜜蜂花会导致戒断反应或成瘾吗？

Does melissa officinalis cause withdrawal or dependence?

作者信息

Demirci Kadir, Akgönül Mehmet, Demirdaş Arif, Akpınar Abdullah

机构信息

Department of Psychiatry, School of Medicine, Süleyman Demirel University, Isparta, Turkey.

出版信息

Med Arch. 2015 Feb;69(1):60-1. doi: 10.5455/medarh.2015.69.60-61. Epub 2015 Feb 21.

DOI:10.5455/medarh.2015.69.60-61
PMID:25870482
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4384870/
Abstract

INTRODUCTION

Melissa officinalis is a medical and aromatic plant that is used for its hypnotic, sedative, and spasmolytic effects. This report presents a case study of30-year-old patient who was admitted to an emergency department with restlessness, tremor, distractibility, and sweating following a discontinuation of Melissa officinalis consumption.

CASE REPORT

In this case, withdrawal symptoms may be related to the dependence effect caused by long-term use of Melissa officinalis. Although Melissa officinalis, a plant, is preferred by many patients as an alternative to pharmaceutical drugs, patients should be made aware that it may have a risk of dependency and can lead to withdrawal symptoms.

摘要

引言

蜜蜂花是一种药用和芳香植物，因其具有催眠、镇静和解痉作用而被使用。本报告介绍了一名30岁患者的病例研究，该患者在停止食用蜜蜂花后，因烦躁不安、震颤、注意力分散和出汗而被送入急诊科。

病例报告

在本病例中，戒断症状可能与长期使用蜜蜂花引起的依赖效应有关。尽管许多患者更喜欢将蜜蜂花这种植物作为药物的替代品，但应让患者意识到它可能存在依赖风险并会导致戒断症状。