Ajayi Olufemi E, Abiodun Olugbenga O, Akintomide Anthony O, Adebayo Rasaaq A, Ogunyemi Suraj A, Balogun Michael O, Bamikole Olaniyi J, Ajibare Adeola O, Ajayi Adesuyi A
Cardiac care unit, Department of Medicine, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Osun State, Nigeria, USA.
Texas Southern University, Houston, TX, USA ; The Saba University School of Medicine, The Bottom, Saba, Dutch Caribbean.
Int J Gen Med. 2015 Mar 26;8:125-30. doi: 10.2147/IJGM.S73216. eCollection 2015.
In patients with heart failure, death is often sudden due to life-threatening arrhythmias. This work was carried out to evaluate the pattern of arrhythmias in Nigerians with heart failure.
Thirty subjects with congestive heart failure (CHF), 30 subjects with hypertensive heart disease, and 15 normal subjects with no obvious features of heart disease were evaluated with resting and 24-hour electrocardiographic monitoring and transthoracic echocardiography. Data were analyzed with one-way analysis of variance with post hoc Duncan's analysis, Fisher's exact test, and linear regression analysis using SPSS version 16.
CHF subjects had more instances of supraventricular tachycardia (P=0.005), ventricular extrasystoles (P<0.001), bigeminy (P<0.001), trigeminy (P<0.001), couplets (P<0.001), triplets (P<0.001), and nonsustained ventricular tachycardia (VT) (P=0.003) than the other two control groups. They also showed a significantly longer VT duration (4.6±5.6 seconds) compared with the other groups (P<0.001). Linear regression analysis showed a significant direct relationship between VT and the maximum number of ventricular extrasystoles per hour (P=0.001).
Cardiac arrhythmias are common in subjects with CHF and are more frequent when compared with patients with hypertensive heart disease and normal subjects.
在心力衰竭患者中,死亡常因危及生命的心律失常而突然发生。本研究旨在评估尼日利亚心力衰竭患者的心律失常模式。
对30例充血性心力衰竭(CHF)患者、30例高血压性心脏病患者和15例无明显心脏病特征的正常受试者进行静息和24小时心电图监测以及经胸超声心动图检查。使用SPSS 16版软件,通过单因素方差分析及事后邓肯分析、费舍尔精确检验和线性回归分析对数据进行分析。
与其他两个对照组相比,CHF患者发生室上性心动过速(P = 0.005)、室性期前收缩(P < 0.001)、成对室性期前收缩(P < 0.001)、三联律(P < 0.001)、二联律(P < 0.001)、三联律(P < 0.001)和非持续性室性心动过速(VT)(P = 0.003)的情况更多。与其他组相比,他们的VT持续时间也明显更长(4.6±5.6秒)(P < 0.001)。线性回归分析显示VT与每小时室性期前收缩的最大数量之间存在显著的直接关系(P = 0.001)。
心律失常在CHF患者中很常见,与高血压性心脏病患者和正常受试者相比更为频繁。