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[儿童化脓性、脓毒症性及过敏性疾病中嗜中性粒细胞功能潜能研究的价值]

[Value of the study of the functional potential of neutrophils in suppurative, septic and allergic diseases in children].

作者信息

Nesterova I V, Svetlichnaia M A

出版信息

Pediatriia. 1989(9):63-5.

PMID:2587172
Abstract

A method for measuring the content of cationic proteins in neutrophil granulocytes of the peripheral blood was employed in patients with pyoseptic (n = 12) and allergic (n = 28) diseases during the exposure to composite infections in vitro. The method enables one to assess the functional potentialities of the cells in mobilizing the internal reserves and the readiness for the trigger of the cellular granular apparatus, for instance during real or predicted exposure of the child to bacterial infections. The determination of the functional potentialities of neutrophil phagocytes can be used as a test for the appraisal of the gravity of allergic and pyoseptic processes as well as for predicting outcomes of pyoseptic diseases.

摘要

采用一种测量外周血中性粒细胞中阳离子蛋白含量的方法,对12例脓毒症患者和28例过敏性疾病患者进行体外复合感染暴露试验。该方法能够评估细胞调动内部储备的功能潜力以及细胞颗粒装置触发的准备情况,例如在儿童实际或预期暴露于细菌感染期间。测定中性粒细胞吞噬细胞的功能潜力可作为评估过敏性和脓毒症过程严重程度以及预测脓毒症疾病预后的一项检测。

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