Hase M, Sako M, Fujii M, Ueda E, Nagae T, Shimizu T, Hirota S, Kono M
Nihon Igaku Hoshasen Gakkai Zasshi. 1989 Sep 25;49(9):1171-3.
Hepatic arterial embolization was performed on VX2 liver tumor of rabbit with subsequent induction heating to the tumor. Prior to the heating, iron particle suspension was injected into tumor tissue as a target of induction heating (500 KHZ, 9 KW). The temperatures of the tumor and liver parenchyma were measured with fluoroptic thermometer. Elevation of the tumor temperature during initial heating for 6 minutes were well correlated to the dose of iron particles injected; 1.4 degrees C with 1 g, 3.0 degrees C with 2 g, and 4.9 degrees C with 3 g. The temperature of liver parenchyma were below 39 degrees C even with 3 g injection.
对兔VX2肝肿瘤进行肝动脉栓塞，随后对肿瘤进行感应加热。加热前，将铁颗粒悬液注入肿瘤组织作为感应加热的靶点（500千赫，9千瓦）。用荧光温度计测量肿瘤和肝实质的温度。初始加热6分钟期间肿瘤温度的升高与注入的铁颗粒剂量密切相关；注入1克时升高1.4摄氏度，注入2克时升高3.0摄氏度，注入3克时升高4.9摄氏度。即使注入3克，肝实质温度仍低于39摄氏度。
