携带d(CT)x.d(AG)x和d(C)n.d(G)n插入片段的超螺旋DNA中B-H转变的能量学
Energetics of the B-H transition in supercoiled DNA carrying d(CT)x.d(AG)x and d(C)n.d(G)n inserts.
作者信息
Lyamichev V I, Mirkin S M, Kumarev V P, Baranova L V, Vologodskii A V, Frank-Kamenetskii M D
机构信息
Institute of Molecular Genetics, USSR Academy of Sciences, Moscow.
出版信息
Nucleic Acids Res. 1989 Nov 25;17(22):9417-23. doi: 10.1093/nar/17.22.9417.
Abstract
We have studied the B-H transition in the d(AG)x inserts of varying length under superhelical stress. The new data and previously published results for the d(G)31 insert are treated within a phenomenological model of the B-H transition, making it possible to obtain, for the first time, the energy parameters of the B-H transition in the d(AG)x and d(G)n sequences.
摘要
我们研究了在超螺旋应力下不同长度的d(AG)x插入片段中的B - H转变。对于d(G)31插入片段的新数据和先前发表的结果，在B - H转变的唯象模型中进行处理，从而首次获得了d(AG)x和d(G)n序列中B - H转变的能量参数。
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