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基于目标诱导的G-四链体形成的铅离子开启式无标记荧光检测

Turn-on and label-free fluorescence detection of lead ions based on target-induced G-quadruplex formation.

作者信息

Xu Lijun, Shen Xiaoqiang, Hong Shanni, Wang Jine, Zhang Yuanyuan, Wang Hongyan, Zhang Jianye, Pei Renjun

机构信息

Key Laboratory of Nano-Bio Interface, Division of Nanobiomedicine, Collaborative Innovation Center of Suzhou Nano Science and Technology, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou, 215123, P. R. China.

出版信息

Chem Commun (Camb). 2015 May 11;51(38):8165-8. doi: 10.1039/c5cc01590a. Epub 2015 Apr 15.

DOI:10.1039/c5cc01590a
PMID:25872736
Abstract

Using a guanine-rich sequence (AGRO100) and N-methyl mesoporphyrin IX (NMM), a turn-on and label-free fluorescent Pb(2+) sensor with high sensitivity and low background fluorescence was presented as a representative of five turn-on sensing systems.

摘要

使用富含鸟嘌呤的序列(AGRO100)和N-甲基中卟啉IX(NMM),构建了一种具有高灵敏度和低背景荧光的开启型无标记荧光Pb(2+)传感器,作为五个开启型传感系统的代表。

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