Bullen Gemma A, Tucker James H R, Peacock Anna F A
School of Chemistry, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
Chem Commun (Camb). 2015 May 11;51(38):8130-3. doi: 10.1039/c5cc01618e. Epub 2015 Apr 15.
The unprecedented use of anthracene photodimerization within a protein or peptide system is explored through its incorporation into a DNA-binding peptide, derived from the GCN4 transcription factor. This study demonstrates an effective and dynamic interplay between a photoreaction and a peptide-DNA assembly, with each process able to exert control over the other.
通过将蒽光二聚作用引入源自GCN4转录因子的DNA结合肽中，探索了其在蛋白质或肽系统中前所未有的应用。这项研究证明了光反应与肽-DNA组装之间有效且动态的相互作用，每个过程都能够对另一个过程施加控制。
