Güneş Mustafa, Umul Mehmet, Altok Muammer, Akyuz Mehmet, İşoğlu Cemal Selcuk, Uruc Fatih, Aras Bekir, Akbaş Alpaslan, Baş Ercan
Department of Urology, Suleyman Demirel University, Faculty of Medicine, Isparta, Turkey.
Department of Urology, Haydarpasa Training and Research Hospital, İstanbul, Turkey.
Korean J Urol. 2015 Apr;56(4):324-9. doi: 10.4111/kju.2015.56.4.324. Epub 2015 Mar 20.
To evaluate the predictive role of the neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), mean platelet volume (MPV), and platelet count (PLT) in the diagnosis of testicular torsion (TT) and testicular viability following TT.
We analyzed two study groups in this retrospective study: 75 patients with a diagnosis of TT (group 1) and 56 age-matched healthy subjects (group 2). We performed a complete blood count as a part of the diagnostic procedure, and NLR, PLR, MPV, and PLT values were recorded. We compared the patient and control groups in terms of these parameters. Then, TT patients were divided into two subgroups according to the time elapsed since the onset of symptoms. Subsequently, we evaluated the relationship between the duration of symptoms and these parameters.
There were significant differences between groups 1 and 2 in NLR, PLR, and PLT (p<0.001 for all). There was no predictive role of MPV in the diagnosis of TT (p=0.328). We determined significantly high sensitivity and specificity levels for NLR in the prediction of TT diagnosis (84% and 92%, respectively). Furthermore, NLR was significantly related to the duration of symptoms in TT patients (p=0.01).
NLR may be a useful parameter in the diagnosis of TT. Furthermore, NLR may be used as a predictive factor for testicular viability following TT.
评估中性粒细胞与淋巴细胞比值(NLR)、血小板与淋巴细胞比值(PLR)、平均血小板体积(MPV)及血小板计数(PLT)在睾丸扭转(TT)诊断及TT后睾丸存活情况预测中的作用。
在这项回顾性研究中,我们分析了两个研究组:75例诊断为TT的患者(第1组)和56例年龄匹配的健康受试者(第2组)。作为诊断程序的一部分,我们进行了全血细胞计数,并记录了NLR、PLR、MPV和PLT值。我们在这些参数方面比较了患者组和对照组。然后,根据症状出现后的时间将TT患者分为两个亚组。随后,我们评估了症状持续时间与这些参数之间的关系。
第1组和第2组在NLR、PLR和PLT方面存在显著差异(所有p<0.001)。MPV在TT诊断中无预测作用(p=0.328)。我们确定NLR在预测TT诊断方面具有显著高的敏感性和特异性水平(分别为84%和92%)。此外,NLR与TT患者的症状持续时间显著相关(p=0.01)。
NLR可能是TT诊断中的一个有用参数。此外,NLR可作为TT后睾丸存活情况的预测因素。